Vaccination for solid organ transplanted patients:Recommendations,efficacy,and safety  

作　　者：Tsvetelina Velikova Stavros Gerasoudis Hristiana Batselova 

机构地区：[1]Medical Faculty,Sofia University St.Kliment Ohridski,Sofia 1407,Bulgaria [2]Faculty of Medicine,Trakia University,Stara Zagora 6000,Bulgaria [3]Department of Epidemiology and Disaster Medicine,Medical University,University Hospital“St George”,Plovdiv 4000,Bulgaria

出　　处：《World Journal of Transplantation》2024年第4期6-14,共9页世界移植杂志

基　　金：the European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.

摘　　要：Solid organ transplant recipients face unique challenges in managing their im-munosuppressed status,making vaccination a critical consideration.This review aimed to comprehensively analyze current recommendations,evaluate the effi-cacy of vaccinations in this population,and assess safety concerns.We explored the latest evidence on vaccine types,timing,and potential benefits for transplant patients,highlighting the importance of individualized approaches for routinely used vaccines as well as coronavirus disease 2019 vaccines.By synthesizing avai-lable data,this review underscored the pressing need to optimize vaccination strategies,ensuring that transplant recipients can obtain the full protection against many pathogens while minimizing risks associated with their post-transplant immunosuppression.

关 键 词：VACCINATION Solid organ transplant IMMUNOSUPPRESSION Transplant reci-pients Vaccine efficacy SAFETY COVID-19 vaccines Immunization strategies Post-transplant immunity Clinical recommendations 

分 类 号：R617[医药卫生—外科学]