Micro-CT探测器不同视野采集对影像学参数的影响  

Influence of diff erent field of view acquisition of Micro-CT detector on imaging parameters

作　　者：雷建锋 王战京 武文琦 毕京东 赵媛媛 Lei Jianfeng;Wang Zhanjing;Wu Wenqi;Bi Jingdong;Zhao Yuanyuan(Central Laboratory of Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学中心实验室,北京100069

出　　处：《现代仪器与医疗》2024年第4期51-55,共5页Modern Instruments & Medical Treatment

摘　　要：目的 基于Micro-CT成像技术,探讨探测器不同的采集视野对影像学参数的影响,以期为Micro-CT离体扫描实验提供合理扫描视野参考。方法 样本选取10只300 g左右的正常SD大鼠离体右下肢的胫骨作为研究对象,从最大探测器采集视野4032×2688开始,在X方向上探测器采集视野按10%递减,建立5组不同采集视野下的大鼠胫骨MicroCT影像图像,根据不同的视野对应定义了组名为A、B、C、D、E,5组影像图像进行影像学参数统计,影像学参数包括图像的SNR、CNR;骨皮质的BMD、BS、BS/BV、Ct.Th;骨小梁的BMD、BV/TV、Tb.Pf、Tb.Th、Tb.N、Tb.Sp。结果 对不同采集视野下的5组数据统计分析后,骨小梁和骨皮质参数分析的组间统计结果差异无统计学意义(P>0.05)。对五组图像的SNR和CNR数据统计后,B、D和E组,在SNR上两两之间比较差异有统计学意义(P <0.05),其余组间在SNR上差异无统计学意义(P>0.05)。CNR组间A和C、D和B、C和E组间差异无统计学意义(P>0.05),其他组间比较差异有统计学意义(P<0.05)。结论 Micro-CT探测器在调整采集视野的情况下,对影像学参数中的骨参数结果不会产生影响,但对影像学中的图像SNR和CNR的信号会产生影响。因此,在Micro-CT成像过程中可以根据实验目的采集样本几何尺寸选择最佳的采集视野。Objective To explore the influence of different acquisition fields on imaging parameters base on Micro-CT imaging technology,so as to provide reasonable scanning field reference for Micro-CT in vitro scanning experiment.Methods Ten normal SD rats' right lower limbs were selected as the research object.Starting from the maximum acquisition field of vision of 4032×2688,the acquisition field of vision of the detector decreased by 10% in the X direction,and five groups of rattibia MicroCT image images were established.According to different acquisition fields,the group names were defined as A,B,C,D and E,and the imaging parameters of the five groups of image images were counted.BMD,BS,BS/BV,CT.Th of bone cortex;BMD,BV/TV,Tb.Pf,Tb.Th,Tb.N,Tb.Sp of trabecular bone.Results After statistical analysis of 5 groups of data under different acquisition fields,the statistical results of bone trabecula and bone cortex parameter analysis were not statistically significant between groups(P > 0.05).After statistical analysis of SNR and CNR data of the five groups,there were significant differences in SNR between groups B,D and E(P < 0.05),while there were no statistically significant differences in SNR among the other groups(P<0.05),while there were no significant differences in SNR among other groups(P>0.05).There was no significant difference between CNR groups A and C,D and B,C and E(P > 0.05),but there were significant differences among other groups(P < 0.05).Conclusion Micro-CT imaging technology will not aff ect the results of bone parameters in imaging parameters,but will aff ect the SNR and CNR signals in imaging.Therefore,in the process of Micro-CT imaging,the best acquisition field of view can be selected according to the geometric size of the samples collected for experimental purposes.

关 键 词：Micro-CT探测器 影像学参数 图像SNR和CNR 骨小梁参数1 

分 类 号：TH77[机械工程—仪器科学与技术] R736.3[机械工程—精密仪器及机械]