结直肠癌术后化疗早期病人益处发现的潜在剖面分析及影响因素  

Latent profile analysis and influencing factors of benefit finding in early stage of postoperative colorectal cancer patients undergoing chemotherapy

作　　者：孙梦莹 荚恒娅 闫红丽 贾园园 任萌萌 SUN Mengying;JIA Hengya;YAN Hongli;JIA Yuanyuan;REN Mengmeng(The First Affiliated Hospital of Naval Medical University,Shanghai 200082 China)

机构地区：[1]海军军医大学第一附属医院,上海200082

出　　处：《护理研究》2024年第17期3052-3058,共7页Chinese Nursing Research

摘　　要：目的:分析结直肠癌术后早期化疗病人益处发现的潜在剖面及影响因素,为制订科学、有效的干预方案提供参考。方法:选取2019年1月—2023年1月海军军医大学第一附属医收治的结直肠癌病人作为研究对象,采用一般资料调查表、疾病获益感量表、生活定向测验问卷修订版、领悟社会支持量表、心理困扰温度计对病人进行调查。使用潜在剖面分析识别病人益处发现特征的类别,Logistic回归分析不同益处发现类别的影响因素。结果:最终纳入203例结直肠癌术后早期化疗病人,其益处发现特征分为3个类别:高益处发现⁃家庭亲密型(54例,占26.6%),中益处发现⁃行为改变型(84例,占41.4%),低益处发现⁃社会关系欠缺型(65例,占32.0%)。与低益处发现⁃社会关系欠缺型比较,生活定向测验问卷修订版得分、领悟社会支持量表越高的病人归属于高益处发现⁃家庭亲密型(OR值为1.987,1.937,P<0.05)和中益处发现⁃行为改变型的概率越大(OR值分别为1.540,1.514,P<0.05),心理困扰温度计得分越低的病人归属于高益处发现⁃家庭亲密型(OR=0.374,P<0.05)和中益处发现⁃行为改变型的概率越大(OR=0.515,P<0.05);男性归属于高益处发现⁃家庭亲密型的概率较大(OR=2.770,P<0.05)。结论:结直肠癌术后早期化疗病人益处发现有高益处发现⁃家庭亲密型、中益处发现⁃行为改变型和低益处发现⁃社会关系欠缺型3种潜在剖面,医护人员应根据其益处发现特征及影响因素,实施针对性干预,以提高其益处发现水平。Objective:To explore the classification and influencing factors of benefit finding in early stage of postoperative colorectal cancer patients undergoing chemotherapy,so as to provide basis for targeted intervention.Methods:Colorectal cancer patients admitted at the First Affiliated Hospital of Naval Medical University from January 2019 to January 2023 were selected as research subjects.The general information questionnaire,Benefit Finding Scale,The Revised Life Orientation,Perceived Social Support Scale and Distress Thermometer were used for investigation.Latent profile analysis was used to explore the latent class of benefit finding,and multinomial Logistic regression analysis was used to compare the characteristics of each latent class.Results:203 postoperative colorectal cancer patients who undergoing chemotherapy were finally enrolled,benefit finding was demonstrated in three different potential classes,named as"high benefit finding⁃family cohesion","medium benefit finding⁃behavioral change"and"low benefit finding⁃lack of social relations",which were 54 cases accounting for 26.6%,84 cases accounting for 41.4%,65 cases accounting for 32.0%,respectively.Compared with the type of"low benefit finding⁃lack of social relations",patients with higher scores of TLOT-R or PSSS were more likely to be classified as"high benefit finding⁃family cohesion"and"medium benefit finding⁃behavioral change"(OR=1.987,1.540,1.937,1.514,P<0.05);patients with lower scores of DT more likely to be classified as"high benefit finding⁃family cohesion"and"medium benefit finding⁃behavioral change"(OR=0.374,0.515,P<0.05);male patients more likely to be classified as"high benefit finding⁃family cohesion"(OR=2.770,P<0.05).Conclusion:There are three latent profiles of benefit finding in postoperative colorectal cancer patients undergoing chemotherapy,which were"high benefit finding-family cohesion","medium benefit finding⁃behavioral change"and"low benefit finding-lack of social relations".Medical staff should implement targete

关 键 词：结直肠癌 化疗 益处发现 影响因素 潜在剖面分析 调查研究 

分 类 号：R473.73[医药卫生—护理学]