医学美容用生物相容性高分子的化工合成与改性  

Chemical Synthesis and Modification of Biocompatible Polymers for Medical Beauty Applications

作　　者：李梦菲 于红静[2] 李志宇[3] LI Meng-fei;YU Hong-jing;LI Zhi-yu(School of Medicine,Zhejiang University,Zhejiang Hangzhou 310000;First People's Hospital of Jiande City,Zhejiang Hangzhou 311600;The Second Affiliated Hospital of School of Medicine of Zhejiang University,Zhejiang Hangzhou 310000,China)

机构地区：[1]浙江大学医学院,浙江杭州310000 [2]建德市第一人民医院,浙江杭州311600 [3]浙江大学医学院附属第二医院,浙江杭州310000

出　　处：《广州化工》2024年第17期1-3,6,共4页GuangZhou Chemical Industry

基　　金：2022年杭州市农业与社会发展科研引导项目(高强度聚焦超声联合直线加速器精准治疗恶性实体瘤的效果评价)(No:20220919Y150)。

摘　　要：生物相容性高分子材料因其优异的生物相容性、可降解性和良好的物理化学性能,在医学美容领域中得到了广泛应用。本文综述了生物相容性高分子材料的定义、分类及其在医学美容中的基本要求,详细探讨了多种高分子材料的化工合成方法,包括聚乳酸(PLA)、聚乙二醇(PEG)、聚氨基酸及其衍生物的合成路线。同时,重点介绍了这些高分子材料的改性技术,如表面改性、物理改性和生物改性,以提升其在医学美容中的应用性能。通过化工合成和改性,生物相容性高分子材料在软组织填充、皮肤修复、抗老化等方面展现出显著优势,以期为进一步优化高分子材料在医学美容领域的应用提供参考。Biocompatible polymer materials have been widely used in the field of medical aesthetics due to their outstanding biocompatibility,degradability,and favorable physical and chemical properties.The definition,classification and basic requirements of biocompatible polymer materials in medical aesthetics was reviewed.The chemical synthesis methods of various polymer materials,including polylactic acid(PLA),polyethylene glycol(PEG),polyamino acids and their derivatives were explored in detail.At the same time,emphasis was placed on the modification techniques of these polymer materials,including surface modification,physical modification and biological modification,to enhance their application performance in medical aesthetics.Through chemical synthesis and modification,biocompatible polymer materials showed significant advantages in soft tissue filling,skin repair,anti-aging and other aspects,with the aim of providing a reference for further optimizing the application of polymer materials in the field of medical beauty.

关 键 词：生物相容性高分子 医学美容 化工合成 改性技术 

分 类 号：R318[医药卫生—生物医学工程]