基于因子分析研究代谢综合征血糖组分异常的证素分布规律  

Study on distribution characteristics of traditional Chinese medicine syndrome of metabolic syndrome with abnormal blood glucose based on factor analysis

作　　者：曾萌薇 潘东豪 江铭倩 许珈齐 夏淑洁 高碧珍[1] ZENG Mengwei;PAN Donghao;JIANG Mingqian;XU Jiaqi;XIA Shujie;GAO Bizhen(Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;The Affliated People's Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China;The Third People's Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)

机构地区：[1]福建中医药大学,福州350122 [2]福建中医药大学附属人民医院,福州350004 [3]福建中医药大学附属第三人民医院,福州350122

出　　处：《中华中医药杂志》2024年第8期4002-4009,共8页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金青年科学基金项目(No.82204977);国家自然科学基金面上项目(No.81873234);福建中医药大学校管课题(No.X2021005)。

摘　　要：目的:分析和探讨代谢综合征血糖组分正常与异常的中医证素分布规律。方法:通过流行病学调查,采集449例代谢综合征患者的四诊信息,基于血糖组分将其分为血糖正常组与血糖异常组,运用因子分析法对获取的症状进行分析,结合专业知识,提取常见的中医证素。结果:通过因子分析,两组各获取17个公因子。经初步分析,病性证素涉及痰湿、火热、气滞、血瘀、气虚、阴虚、阳虚等,病位证素主要有脾、肝、肾、心等,且两组的证素和症状分布具有一定差异(P<0.05)。结论:基于因子分析对代谢综合征患者四诊信息进行分析,对本病血糖组分异常的中医证素分布规律研究有一定参考价值。Objective:To analyze and explore the the traditional Chinese medicine(TCM)syndrome distribution characteristics of normal and abnormal glycemic level in metabolic syndrome(MS).Methods:By epidemiological survey method,the four diagnostic information of 449 patients with metabolic syndrome were collected,and they were divided into normal and abnormal groups based on glycemic level,and the obtained symptoms were analyzed by using factor analysis method.We extracted common Chinese medical evidence elements by combining with professional knowledge.Results:Through factor analysis,17 common factors were obtained in each of the two groups.After preliminary analysis,the main syndrome elements involved phlegm-dampness,fire-heat,qi stagnation,blood stasis,qi deficiency,yin deficiency,yang deficiency,etc.,the main locationelements involed spleen,liver,kidney,and heart,etc..The distribution of syndrome elements and symptoms in the two groups had a certain degree of differences(P<0.05).Conclusion:Based on factor analysis of the four diagnostic information of patients with metabolic syndrome,it has some reference value for the study of TCM syndrome distribution characteristics at glycemic level of this disease.

关 键 词：代谢综合征 血糖组分 因子分析 证素 

分 类 号：R259[医药卫生—中西医结合]