生命早期不良暴露与子代视力异常的研究进展  

Research progress of adverse exposure in early life and abnormal visual acuity in offspring

作　　者：刘诗音 游雪 林晓妍 麦凯童 刘星彤 曹梦婷 杜江波 LIU Shiyin;YOU Xue;LIN Xiaoyan;MAI Kaitong;LIU Xingtong;CAO Mengting;DU Jiangbo(The First School of Clinical Medicine,Nanjing Medical Univer-sity,Nanjing(210029),Jiangsu Province,China;不详)

机构地区：[1]南京医科大学第一临床医学院,江苏210029 [2]南京医科大学公共卫生学院流行病学系/全球健康研究中心 [3]南京医科大学生殖医学与子代健康全国重点实验室

出　　处：《中国学校卫生》2024年第8期1203-1207,共5页Chinese Journal of School Health

基　　金：国家重点研发计划项目(2021YFC2700705);大学生创新创业训练计划项目(202310312014Z)。

摘　　要：近年来,儿童眼部疾病的防治已成为全球范围内广泛关注的公共卫生问题之一。由于遗传因素与环境因素均可影响子代视觉系统的形成,导致屈光不正、斜视、眼球震颤等视力异常情况出现。文章从孕期烟草暴露、微量元素暴露、妊娠期糖尿病、妊娠期高血压及孕期药物滥用等方面对生命早期暴露与子代视力结局的研究进行总结,旨在阐明生命早期不良暴露与子代视力结局的影响因素及其机制,为制定更有效的儿童青少年眼部疾病防治策略提供科学依据。In recent years,the prevention and treatment of eye diseases in children has become one of the worldwide recognized public health issues.Both genetic and environmental factors can influence the development of offspring visual systems,leading to abnormal vision acuity such as refractive errors,strabismus,and nystagmus.With the aim of elucidating the influencing factors and mechanisms of early life adverse exposures on offspring vision outcomes,the article summarizes the research on exposure in early life and visual acuity in offspring from different perspectives,including tobacco exposure during pregnancy,exposure to microelements,gestational diabetes,gestational hypertension,and drug abuse during pregnancy,so as to provide scientific evidence for the development of more effective strategies to prevent and control eye diseases in children and adolescents.

关 键 词：烟草 微量营养系 糖尿病 妊娠 高血压 妊娠性 视力 低 儿童 

分 类 号：R179[医药卫生—妇幼卫生保健] R778.1[医药卫生—公共卫生与预防医学] R771R715.3