白藜芦醇纳米微粒新型给药系统研究进展  

Advances in Novel Drug Delivery Systems for Resveratrol Nanoparticles

作　　者：王振涛 WANG Zhentao(School of Pharmacy,Changde Vocational Technical College,Changde 415000,China)

机构地区：[1]常德职业技术学院药学系,湖南常德415000

出　　处：《化工管理》2024年第25期143-146,共4页Chemical Management

基　　金：湖南省教育厅科学研究项目(23C0479);常德市科技创新指导性项目(2023ZD17)。

摘　　要：白藜芦醇是一种植物来源的多酚类化合物,具有抗炎、抗肿瘤等多种药理作用,长期以来其水溶解度低、稳定性差的问题限制了其临床开发。纳米给药系统可以提高难溶性药物的生物利用度、稳定性,近年来,研究人员设计了多种类型的纳米给药系统,提高了白藜芦醇的生物利用度。现文章综述近年来白藜芦醇纳米微粒新型给药系统研究进展,旨在为其在临床开发与应用提供新的思路。Resveratrol is a kind of plant-derived polyphenol compound,which has many pharmacological effects such as anti-inflammatory and anti-tumor.For a long time,its low water solubility and poor stability have limited its clinical development.Nano drug delivery system can improve the bioavailability and stability of insoluble drugs.In recent years,researchers have designed many types of nanodrug delivery systems to improve the bioavailability of resveratrol.This paper reviews the recent research progress of novel drug delivery system for resveratrol nanoparticles,aiming to provide new ideas for its clinical development and application.

关 键 词：白藜芦醇 纳米微粒 聚合物纳米粒 纳米晶体 新型给药系统 

分 类 号：R94[医药卫生—药剂学]