基于“壮火食气”理论的清源扶正法治疗湿热蕴结型急性痛风性关节炎的临床疗效  

Clinical efficacy of Qingyuan Fuzheng method based on the theory of"Zhuang fire and food Qi"in the treatment of acute gouty arthritis of damp-heat accumulation type

作　　者：伍丽 韩洁 杜曜宇 余敏 WU Li;HAN Jie;DU Yaoyu;YU Min(Department of Rheumatology,Guangzhou University of Chinese Medicine Affiliated Hospital Chongqing Hospital,Chongqing 400700,China;Graduate School of Guangzhou University of Traditional Chinese Medicine,Guangzhou,Guangdong 510006,China;Department of Acupuncture and Moxibustion,Guangzhou University of Chinese Medicine Affiliated Hospital Chongqing Hospital,Chongqing 400700,China)

机构地区：[1]广州中医药大学第一附属医院重庆医院风湿病科,重庆400700 [2]广州中医药大学研究生院,广东广州510006 [3]广州中医药大学第一附属医院重庆医院针灸科,重庆400700

出　　处：《检验医学与临床》2024年第18期2685-2689,共5页Laboratory Medicine and Clinic

基　　金：重庆市科卫联合中医药科研项目(2020ZY4043)。

摘　　要：目的分析基于“壮火食气”理论的清源扶正法治疗湿热蕴结型急性痛风性关节炎的临床疗效。方法选取2022年9月至2023年12月在广州中医药大学第一附属医院重庆医院就诊的70例湿热蕴结型急性痛风性关节炎患者,按照随机数字表法分为对照组和试验组,每组35例。对两组均进行健康教育并给予秋水仙碱治疗。对照组病灶局部予以宣痹清消散治疗,试验组在对照组的基础上加艾灸双侧“脾俞”治疗。比较两组治疗前后急性痛风性关节炎患者各项中医症候评分、实验室指标[红细胞沉降率(ESR)、C-反应蛋白(CRP)、尿酸(UA)]、影像学指标(关节滑膜厚度分级、关节腔积液分级)及疗效。结果试验组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组各项中医证候评分及关节滑膜厚度、关节腔积液分级和ESR、CRP、UA水平比治疗前低,且试验组低于对照组,差异均有统计学意义(P<0.05)。结论基于“壮火食气”理论的清源扶正法治疗湿热蕴结型急性痛风性关节炎的疗效确切,为中医治疗湿热蕴结型急性痛风性关节炎提供了标本兼治的新思路。Objective To analyze the clini cal efficacy of Qingyuan Fuzheng method based on the theory of"Zhuang fire and food Qi"in the treatment of acute gouty arthritis of damp-heat accumulation type.Methods Seventy patients with acute gouty arthritis of damp-heat accumulation type combination in Guangzhou University of Chinese Medicine Affiliated Hospital Chongqing Hospital from September 2022 to December 2023 were randomly divided into control group and experimental group,with 35 cases in each group.Both groups were given health education and colchicine treatment.The control group was treated with Xuanbiqing dissipating treatment,and the experimental group was treated with moxibustion at bilateral"Pishu"on the basis of the control group.The Traditional Chinese Medicine Syndrome Score of acute gouty arthritis,laboratory indexes[erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),uric acid(UA)],imaging indexes(joint synovial thickness grade,joint effusion grade)and curative effect in patients with acute gouty arthritis were compared between the two groups before and after treatment.Results The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the Traditional Chinese Medicine Syndrome Score,joint synovial thickness grade,joint effusion grade,ESR,CRP and UA levels of the two groups were lower than those before treatment,and those of the experimental group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion The Qingyuan Fuzheng method based on the theory of"Zhuang fire and food Qi"is effective in the treatment of acute gouty arthritis with damp-heat accumulation type,which provides a new idea for treating both symptoms and root causes of acute gouty arthritis with damp-heat accumulation.

关 键 词：急性痛风性关节炎 湿热蕴结 壮火食气 宣痹清消散 脾俞 随机对照试验 

分 类 号：R246[医药卫生—针灸推拿学]