扁桃体腺样体肥大患儿使用低温等离子扁桃体腺样体切除术进行治疗效果分析  

Analysis of the Therapeutic Effect of Low-Temperature Plasma Tonsillectomy on Children with Adenoid Hypertrophy of the Tonsils

作　　者：周志存 林春裕 ZHOU Zhicun;LIN Chunyu(Department of Otorhinolaryngology,Dehua County Hospital,Fujian Province,Quanzhou 362500,China;Department of Pediatrics,Dehua County Hospital,Fujian Province,Quanzhou 362500,China)

机构地区：[1]福建省德化县医院耳鼻喉科,泉州362500 [2]福建省德化县医院儿科,泉州362500

出　　处：《中国医药指南》2024年第26期81-84,共4页Guide of China Medicine

摘　　要：目的探讨扁桃体腺样体肥大患儿应用扁桃体腺样体低温等离子(LTP)切除术治疗的效果。方法选择本院收治的扁桃体腺样体肥大患儿研究,126例,于2022年2月至2024年2月入组。随机数字表法分为两组,分别为常规手术(对照组,n=63)、LTP切除术(LTP组,n=63)。对比围手术期指标、并发症、术后不同时点疼痛程度,术前与术后3 d创伤应激指标与CC类趋化因子,以及术前与术后1周睡眠质量。结果围手术期指标对比,两组白膜完全消退时间无差异(P>0.05),但LTP组手术时间、手术出血量、术后饮食恢复正常时间低于对照组(P<0.05);术后1 d、3 d、5 d,LTP组疼痛评分低于对照组(P<0.05);术前,两组创伤应激指标与CC类趋化因子无差异(P>0.05),术后3 d与对照组比较,LTP组创伤应激指标(PCT、Cor、PGE2、PGF2α)更低,而CC类趋化因子CCL2更高、CCL21更低(P<0.05);术后1周LTP组睡眠质量优于对照组(P<0.05);LTP组并发症率低于对照组(P<0.05)。结论LTP切除术用于扁桃体腺样体肥大患儿中,与常规手术比较,有助于减轻创伤应激反应,减轻术后疼痛,减少手术时间与术后恢复时间,减少手术出血,而且还可更好地缓解术后睡眠质量,促进CC类趋化因子水平改善,对降低并发症率也有积极的意义。Objective To explore the therapeutic effect of low-temperature plasma(LTP)tonsillectomy on children with adenoid hypertrophy.Methods A study was conducted on pediatric patients with adenoid hypertrophy of the tonsils admitted to our hospital,with 126 cases.They were enrolled from February 2022 to February 2024.The random number table method was used to divide patients into two groups,namely conventional surgery(control group,n=63)and LTP resection surgery(LTP group,n=63).Compare perioperative indicators,complications,postoperative pain levels at different time points,preoperative and postoperative trauma stress indicators and CC chemokines,as well as preoperative and postoperative sleep quality for one week.All data were entered into an Excel spreadsheet and analyzed using SPSS 23.0 statistical software.Results Perioperative indexes showed no difference between the two groups(P>0.05),but the operative time,the amount of blood loss and the time of dietary normalcy in LTP group were lower than those in control group(P<0.05).The pain score of LTP group was lower than that of control group on day 1,day 3 and day 5 after operation(P>0.05).Before surgery,there was no difference between the two groups in traumatic stress index and CC chemokines(P>0.05).Compared with the control group,LTP group had lower traumatic stress index(PCT,Cor,PGE2,PGF2α),while CC chemokines CCL2 were higher and CCL21 were lower(P>0.05).The sleep quality of LTP group was better than that of control group one week after operation(P>0.05).The complication rate of LTP group was lower than that of control group(P>0.05).Conclusions Compared with conventional surgery,LTP resection is helpful in reducing traumatic stress response,postoperative pain,surgical time and recovery time,and surgical bleeding in children with adenoid hypertrophy of the tonsils.It can also better alleviate postoperative sleep quality,promote the improvement of CC class chemokine levels,and have a positive significance in reducing the incidence of complications.It is worthy of c

关 键 词：扁桃体腺样体肥大 低温等离子切除术 疼痛 创伤应激指标 CC类趋化因子 并发症 

分 类 号：R766[医药卫生—耳鼻咽喉科] R726.1[医药卫生—临床医学]