舒芬太尼复合布比卡因腰硬联合麻醉在剖宫产患者中的应用效果  

Effects of Sufentanil combined with Bupivacaine for combined spinal-epidural anesthesia in patients undergoing cesarean section

作　　者：左珊珊 ZUO Shanshan(Department of Anesthesiology of Zhengzhou Central Hospital,Zhengzhou 450000 Henan,China)

机构地区：[1]郑州市中心医院麻醉科,河南郑州450000

出　　处：《中国民康医学》2024年第18期67-70,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察舒芬太尼复合布比卡因腰硬联合麻醉在剖宫产患者中的应用效果。方法:选取2021年1月至2022年11月该院收治的86例剖宫产患者进行前瞻性研究,按照随机数字表法分为研究组与对照组各43例。对照组采用布比卡因腰硬联合麻醉,研究组采用舒芬太尼复合布比卡因腰硬联合麻醉,比较两组麻醉起效时间、达到最高麻醉平面时间、痛觉恢复时间、生命体征指标水平、应激指标水平以及不良反应发生率。结果:研究组麻醉起效时间、达到最高麻醉平面时间均短于对照组,痛觉恢复时间长于对照组,差异有统计学意义(P<0.05);麻醉15 min、手术结束时,两组平均动脉压、心率、血氧饱和度等生命体征指标水平低于麻醉前,但研究组高于对照组,差异均有统计学意义(P<0.05);麻醉后24 h,两组血清去甲肾上腺素、皮质醇、P物质等应激指标水平高于麻醉前,但研究组低于对照组,差异均有统计学意义(P<0.05);研究组不良反应发生率为9.30%,明显低于对照组的25.58%,差异有统计学意义(P<0.05)。结论:舒芬太尼复合布比卡因腰硬联合麻醉应用于剖宫产患者可缩短麻醉起效时间和达到最高麻醉平面时间,延长痛觉恢复时间,提高生命体征指标水平,以及降低应激指标水平和不良反应发生率,效果优于单纯布比卡因腰硬联合麻醉。Objective:To observe effects of Sufentanil combined with Bupivacaine for combined spinal-epidural anesthesia in patients undergoing cesarean section.Methods:A prospective study was conducted on 86 patients with cesarean section admitted to the hospital from January 2021 to November 2022.According to the random number table method,they were divided into study group and control group,43 cases in each group.The control group was treated with Bupivacaine combined spinal-epidural anesthesia,while the study group was treated with Sufentanil combined with Bupivacaine combined spinal-epidural anesthesia.The onset time of anesthesia,the time to reach the highest anesthesia plane,the recovery time of pain,the levels of vital signs,the levels of stress indicators,and the incidence of adverse reactions were compared between the two groups.Results:The onset time of anesthesia and the time to reach the highest anesthesia plane in the study group were shorter than those in the control group,the recovery time of pain was longer than that in the control group,and the differences were statistically significant(P<0.05).15 min after anesthesia and at the end of the surgery,the levels of vital signs such as mean arterial pressure,heart rate and blood oxygen saturation in the two groups were lower than those before anesthesia,but those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).24 h after anesthesia,the levels of stress indicators such as serum norepinephrine,cortisol and substance P in the two groups were higher than those before anesthesia,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the incidence of adverse reactions in the study group was 9.30%,which was significantly lower than 25.58%in the control group,and the difference was statistically significant(P<0.05).Conclusions:Sufentanil combined with Bupivacaine for combined spinal-epidural anesthesia in the patie

关 键 词：剖宫产 腰硬联合麻醉 布比卡因 舒芬太尼 生命体征 应激 不良反应 

分 类 号：R614[医药卫生—麻醉学]