Antibacterial Activity of Plants in Cirsium:A Comprehensive Review  

作　　者：TANG Xiao-meng XIE Ming-xia GOU Jun-li CHEN Liang TIAN Jin-long ZHANG Xia LU You-yuan WANG Han-qing 

机构地区：[1]College of Pharmacy,Ningxia Medical University,Yinchuan,Ningxia,750004,China [2]College of Traditional Chinese Medicine,Hunan University of Chinese Medicine,Changsha,410007,China [3]General Hospital of Ningxia Medical University,Yinchuan,Ningxia,750004,China [4]Ningxia Regional Characteristic Traditional Chinese Medicine Collaborative Innovation Center Co-constructed by the Province and Ministry,Ningxia Engineering and Technology Research Center for Modernization of Regional Characteristic Traditional Chinese Medicine,Ningxia Medical University,Yinchuan,750004,China [5]Key Laboratory of Ningxia Minority Medicine Modernization,Ministry of Education,Yinchuan,750004,China

出　　处：《Chinese Journal of Integrative Medicine》2024年第9期835-841,共7页中国结合医学杂志（英文版）

摘　　要：As ethnic medicine,the whole grass of plants in Cirsium was used as antimicrobial.This review focuses on the antimicrobial activity of plants in Cirsium,including antimicrobial components,against different types of microbes and bacteriostatic mechanism.The results showed that the main antimicrobial activity components in Cirsium plants were flavonoids,triterpenoids and phenolic acids,and the antimicrobial ability varied according to the species and the content of chemicals.Among them,phenolic acids showed a strong antibacterial ability against Acinetobacter baumannii,Pseudomonas aeruginosa,and Enterococcus faecium.The antibacterial mechanisms include:(1)damaging the cell membrane,cell walls,mitochondria and nucleus of bacteria;(2)inhibiting the synthesis of proteins and nucleic acids;(3)suppressing the synthesis of enzymes for tricarboxylic acid cycle pathways and glycolysis,and then killing the bacteria via inhibition of energy production.Totally,most research results on antimicrobial activity of Cirsium plants are reported based on in vitro assays.The evidence from clinical data and comprehensive evaluation are needed.

关 键 词：CIRSIUM traditional use antibacterial active components bacteriostatic activity bacteriostatic mechanism Chinese medicine 

分 类 号：R285[医药卫生—中药学]