急诊冠脉再通后主动脉内球囊反搏治疗急性心肌梗死合并心源性休克患者的效果及对生存率的影响  

Effect of intra-aortic balloon pump after emergency coronary re-canalization in the treatment of patients with acute myocardial infarction complicated with cardiogenic shock and its influence on survival rate

作　　者：罗俊妮 张倩 LUO Junni;ZHANG Qian(Cardiology Department,Baoji Second People's Hospital,Baoji 721000,China)

机构地区：[1]宝鸡市第二人民医院心内科,陕西宝鸡721000

出　　处：《临床医学研究与实践》2024年第26期70-73,共4页Clinical Research and Practice

摘　　要：目的分析急诊冠脉再通后主动脉内球囊反搏(IABP)对急性心肌梗死(AMI)合并心源性休克(CS)患者预后的影响。方法选取2020年1月至2023年1月我院接收的140例AMI合并CS患者作为研究对象,以入院先后顺序将其分为对照组和研究组,各70例。对照组给予常规治疗+经皮冠状动脉介入(PCI)治疗,研究组给予PCI+IABP治疗。比较两组的心功能指标、血清心肌损伤指标、临床疗效及生存率。结果治疗后,研究组的左室收缩期末内径(LVESD)、左室舒张期末内径(LVEDD)均低于对照组,左室射血分数(LVEF)、心脏指数(CI)均高于对照组(P<0.05)。治疗后,研究组的心肌肌钙蛋白I(c Tn I)、肌酸激酶同工酶(CK-MB)、血乳酸(Lac)、N末端脑钠肽前体(NT-proBNP)水平均低于对照组(P<0.05)。研究组的治疗总有效率、存活率高于对照组(P<0.05)。结论急诊冠脉再通后IABP治疗AMI合并CS能够减轻患者的心肌功能损伤,促进心功能显著改善,有效提高患者的临床疗效及存活率,具有较高的临床应用价值,值得推广和应用。Objective To analyze the effect of intra-aortic balloon pump(IABP)after emergency coronary re-canalization on the prognosis of patients with acute myocardial infarction(AMI)complicated with cardiogenic shock(CS).Methods A total of 140 patients with AMI complicated with CS received in our hospital from January 2020 to January 2023 were selected as the research objects,and the patients were divided into control group and study group according to the order of admission,with 70 cases in each group.The control group was treated with conventional therapy+percutaneous coronary intervention(PCI),and the study group was treated with PCI+IABP.The cardiac function indexes,serum myocardial injury indexes,clinical efficacy and survival rate were compared between the two groups.Results After treatment,the left ventricular end systolic diameter(LVESD)and left ventricular end diastolic diameter(LVEDD)in the study group were lower than those in the control group,and the left ventricular ejection fractions(LVEF)and cardiac index(CI)were higher than those in the control group(P<0.05).After treatment,the levels of cardiac troponin I(cTnI),creatine kinase isoenzyme(CK-MB),blood lactic acid(Lac)and N-terminal pro-brain natriuretic peptide(NT-proBNP)in the study group were lower than those in the control group(P<0.05).The total effective rate and survival rate of the study group were higher than those of the control group(P<0.05).Conclusion IABP after emergency coronary re-canalization in the treatment of AMI combined with CS can reduce the myocardial function injury of patients,promote the improvement of cardiac function,and effectively improve the clinical treatment effect and survival rate of patients.It has high clinical application value and is worthy of promotion and application.

关 键 词：急性心肌梗死 心源性休克 经皮冠状动脉介入 主动脉内球囊反搏 

分 类 号：R541.64[医药卫生—心血管疾病]