阵发性心房颤动进展为持续性心房颤动的危险因素分析  

Risk factors for progression fromparoxysmal atrial fibrillation to persistent atrial fibrillation

作　　者：贾秋蕾 杨亦含 胡元会[2] 陈婷 段成林 杜宜航 袁果真 Jia Qiulei;Yang Yihan;Hu Yuanhui;Chen Ting;Duan Chenglin;Du Yihang;Yuan Guozhen(Department of Cardiovascular Medicine,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 101121,China;不详)

机构地区：[1]北京中医药大学东直门医院心血管科四区,北京101121 [2]中国中医科学院广安门医院心内科,北京100053 [3]西安市中医医院心血管科,西安710000

出　　处：《中国循证心血管医学杂志》2024年第7期834-836,849,共4页Chinese Journal of Evidence-Based Cardiovascular Medicine

基　　金：首都卫生发展科研专项(首发2022-1-4153)。

摘　　要：目的探讨阵发性心房颤动进展为持续性心房颤动的危险因素。方法连续选择2016年1月至2021年10月期间于广安门医院心内科病房收治的确诊为非瓣膜性心房颤动患者782例,分为持续性心房颤动组(n=399)和阵发性心房颤动组(n=383),使用Logistic回归评估持续性心房颤动的危险因素。结果持续性心房颤动组年龄(P<0.001)、左心房内径(LA,P<0.001)大于阵发性心房颤动患者,合并冠心病(P<0.001)、心力衰竭(P<0.05)、缺血性卒中(P<0.01)、糖尿病(P<0.05)、高尿酸血症(P<0.001)、慢性肾功能不全(P<0.001)等疾病的比例较阵发性心房颤动患者高。Logistic回归分析提示LA≥40 mm(OR=6.40,95%CI:4.35~9.40,P<0.001)、合并冠心病(OR=1.56,95%CI:1.09~2.22,P<0.05)是持续性心房颤动的独立危险因素。结论冠心病和左房内径增大是阵发性心房颤动进展为持续性心房颤动的独立危险因素。Objective To discuss the risk factors for progression fromparoxysmal atrial fibrillation(PAF)to persistent atrial fibrillation(PeAF).Methods The patients with non-valvular atrial fibrillation(NVAF,n=782)were chosen from Department of Internal Medicine in Guang`anmen Hospital from Jan.2016 to Oct.2021.The patients were divided into PeAF group(n=399)and PAF group(n=383).The risk factors for PeAF were assessed by using Logistic regression analysis.Results The age,left atrial diameter(LA,P<0.001),and percentages of complicated coronary heart disease(CHD,P<0.001),heart failure(HF,P<0.05),ischemic stroke(P<0.01),diabetes(P<0.05),hyperuricemia(P<0.001)and chronic renal insufficiency(CRI,P<0.001)were higher in PeAF group than those in PAF group.The results of Logistic regression analysis showed that LA≥40 mm(OR=6.40,95%CI:4.35~9.40,P<0.001)and complicated CHD(OR=1.56,95%CI:1.09~2.22,P<0.05)were independent risk factors for PeAF.Conclusion CHD and increased LA are independent risk factors for the progression from PAFtoPeAF.

关 键 词：阵发性心房颤动 持续性心房颤动 冠心病 左房内径 危险因素 

分 类 号：R541.75[医药卫生—心血管疾病]