急性三氟化氮中毒致高铁血红蛋白血症和溶血性贫血1例  

One case of methemoglobinemia and hemolytic anemia caused by acute nitrogen trifluoride poisoning

作　　者：刘学[1] 尚波[1] 牛燕英[1] Liu Xue;Shang Bo;Niu Yanying(Occupational Disease DepartmentⅡ,Shandong Zibo Occupational Disease Prevention and Control Hospital,Zibo 255000,China)

机构地区：[1]山东省淄博市职业病防治院职业病二科,淄博255000

出　　处：《中华劳动卫生职业病杂志》2024年第8期624-626,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：本文对1例急性三氟化氮中毒致高铁血红蛋白血症、溶血性贫血患者的发病过程、临床特点、治疗措施及预后进行分析。患者职业暴露三氟化氮,发病后立即就诊,监测高铁血红蛋白并进行全面检查,综合分析后考虑急性三氟化氮中毒致高铁血红蛋白血症、溶血性贫血及肝损伤。脱离接触,给予氧疗、亚甲蓝、小剂量甲泼尼龙、维生素C、还原性谷胱甘肽等对症治疗,患者预后较好,为三氟化氮中毒的临床救治及职业健康检查提供参考。This paper analyzes the pathogenesis,clinical characteristics,treatment measures and prognosis of a case of methemoglobin and hemolytic anemia caused by acute nitrogen trifluoride poisoning.The patient with occupational exposure to nitrogen trifluoride was treated immediately after the onset of illness,methemoglobin was monitored and a comprehensive examination was conducted.After comprehensive analysis,it was considered that acute nitrogen trifluoride poisoning could cause methemoglobinemia,hemolytic anemia and liver injury.The patient was disengaged and given symptomatic treatment such as oxygen therapy,methylene blue,low-dose methylpredrone,vitamin C and reduced glutathione.The prognosis of the patient is good,which provides a reference for the clinical treatment and occupational health examination of nitrogen trifluoride poisoning.

关 键 词：中毒 三氟化氮 职业暴露 高铁血红蛋白血症 溶血性贫血 

分 类 号：R135.14[医药卫生—劳动卫生]