亚低温下超长心肺脑复苏成功救治体会  

Experience of successful treatment of ultra-long cardiopulmonary and brain resuscitation under mild hypothermia

作　　者：范远华 叶志梅 李晓 汤彦 Fan Yuanhua;Ye Zhimei;Li Xiao;Tang Yan(Department of Emergency,Qingpu Branch of Zhongshan Hospital Affiliated with Fudan University,Shanghai 201700,China)

机构地区：[1]复旦大学附属中山医院青浦分院急诊科,上海201700

出　　处：《中国中西医结合急救杂志》2024年第3期350-352,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：上海市重点专科建设项目(ZK2019807)。

摘　　要：目的报告1例2次心搏骤停J波综合征患者的救治经过,探讨亚低温治疗在心肺脑复苏中的作用。方法复旦大学附属中山医院青浦分院急诊科2021年9月30日收治1例院外心搏骤停J波综合征患者,在治疗过程中采取亚低温脑保护措施,院内再次发生心搏骤停,在亚低温状态下持续进行了长达230 min的心肺复苏(CPR)后恢复窦性心律,最终患者救治成功,未遗留任何神经系统后遗症,现介绍临床诊治过程,分享救治体会。结果患者女性,17岁,因跑步后突发意识丧失30 min于2021年9月30日入院。既往曾有运动后或紧张后晕厥3次。此次晕厥后立即进行徒手CPR,10 min后救护车到达现场,给予电击除颤及气管插管机械通气。入住重症监护病房(ICU)时患者持续强直性抽搐,给予镇静、抗癫痫、维持内环境稳定等,同时给予亚低温治疗,控制体温在34~36℃,夜间强直抽搐逐渐缓解。10月1日11:40心电监护提示心室纤颤(室颤),立即给予CPR、电除颤、升压等抢救。因反复室颤,反复行电击除颤,同时采用心肺复苏机进行胸外按压,给予利多卡因抗心律失常,肾上腺素、异丙肾上腺素维持心率90次/min以上,15:30左右心律趋于稳定,血压逐渐改善。复苏成功后继续亚低温等脑保护治疗,10月4日意识转清,10月6日肌力基本恢复正常,拔除气管插管。动态心电图检查提示V1~V3 ST段抬高,结合患者反复晕厥病史,既往心电图提示早期复极,考虑J波综合征,Brugada综合征可能,安装植入型心律转复除颤器(ICD)后出院。结论本例患者2次心搏骤停均复苏成功,其中院内心搏骤停后CPR在亚低温状态下进行超长时间心肺脑复苏成功,未遗留神经系统后遗症,其救治经验为临床心肺脑复苏提供了参考。Objective This case report describes the treatment of a patient with J-wave syndrome who experienced two cardiac arrests and discusses the potential role of mild hypothermia in cardiopulmonary and cerebral resuscitation.Methods A patient with J-wave syndrome was admitted to the department of emergency of Qingpu Branch of Zhongshan Hospital Affiliated with Fudan University.During the treatment,mild hypothermia was adopted for brain protection.The patient suffered cardiac arrest again in the hospital.After continuous cardiopulmonary resuscitation(CPR)for 230 minutes under mild hypothermia,sinus rhythm was restored.By sharing the diagnostic approach and treatment process,valuable insights can be gained to improve patient outcomes in similar cases.Results A 17-yearold female patient was admitted to department of emergency of Qingpu Branch of Zhongshan Hospital Affiliated with Fudan University on September 30,2021 due to sudden loss of consciousness for 30 minutes after running.She fainted 3 times in the past after excise and nervousness.CPR was performed immediately after the syncope,and an ambulance arrived at the scene 10 minutes later,and electrical defibrillation and tracheal intubation mechanical ventilation were conducted.When admitted to the intensive care unit(ICU),the patient continued to have tetanic convulsions.To manage these symptoms,the medical team administered sedation and anti-epileptic treatment while focusing on maintaining internal environment stability.Additionally,mild hypothermia treatment was initiated,controlling the patient's core body temperature at 34-36℃.With these interventions,the tetanic convulsions gradually subsided during the night.At 11:40 on October 1,the electrocardiogram(ECG)monitoring indicated ventricular fibrillation,and immediate rescue efforts such as CPR,electrical defibrillation,and blood pressure elevation were given.Due to recurrent ventricular fibrillation,the patient underwent repeated shock defibrillation and chest compressions with the CPR machine.Antiarrhythmic l

关 键 词：心搏骤停 超长心肺脑复苏 亚低温治疗 体表降温法 

分 类 号：R605.974[医药卫生—急诊医学]