槐米刺梨的抗敏止痒效果及其在辅食营养素撒剂中的应用  

Antiallergic and Antipruritic Effects of Sophora Japonica L.&Rosa Roxburghii Extract and Its Application in Supplementary Food Nutrient Spraying

作　　者：丁丽丽 王文风 陈思 董福月 王阳光 张琳琳 DING Lili;WANG Wenfeng;CHEN Si;DONG Fuyue;WANG Yangguang;ZHANG Linlin(Weihai Ziguang Youjian Technology Co.,LTD,Weihai 264206,Shandong,China;Weihai Ziguang Technology Park Co.,LTD,Weihai 264206,Shandong,China)

机构地区：[1]威海紫光优健科技股份有限公司,山东威海264206 [2]威海紫光科技园有限公司,山东威海264206

出　　处：《中央民族大学学报（自然科学版）》2024年第3期5-13,共9页Journal of Minzu University of China(Natural Sciences Edition)

基　　金：山东省创新项目-辅食营养补充品工艺改善研究(201940510002)。

摘　　要：探讨槐米刺梨组合物在抗过敏止痒中的作用效果,并将其应用在辅食营养素撒剂中,旨在为易过敏、免疫力低下的婴幼儿提供其所需的营养方案。本研究设置不同实验组,通过测定透明质酸酶活性抑制率,给药后各组小鼠耳肿胀度,脾脏指数,胸腺指数及小鼠舔体次数,考察槐米刺梨组合物的抗过敏和止痒效果;将槐米刺梨组合物应用在辅食营养素撒剂中,考察该辅食营养素撒剂的混合均匀度及加速过程中各营养素的稳定性。结果表明,槐米刺梨组合物对透明质酸酶活性抑制率为73%,与模型组相比槐米刺梨组合物能显著降低耳肿胀度,脾脏指数,胸腺指数及小鼠舔体次数,证明槐米刺梨组合物具有较好的抗过敏和止痒效果;槐米刺梨组合物辅食营养素撒剂中各营养素的RSD值均<5%,各营养素在加速6个月内的衰减情况稳定,符合国家标准要求。本研究验证了槐米刺梨组合物具有抗过敏止痒效果,并预测了该组合物辅食营养素撒剂中各营养素衰减情况,为抗过敏止痒辅食营养素撒剂产品研发提供一定的数据支持和参考依据。To investigate the effect of Sophora japonica L.&Rosa roxburghii extract on anti⁃allergy and anti⁃itch,and apply it in complementary food nutrient powder,aiming to provide nutrition pro⁃gram for infants and young children who are prone to allergy and low immunity.In this study,differ⁃ent experimental groups were set up to investigate the antiallergic and antipruritic effects of Sophora japonica L.&Rosa roxburghii extract by measuring the inhibition rate of hyaluronidase activity,ear swelling,spleen index,thymus index and licking times of mice in each group after administration.The composition of Sophora japonica L.and Rosa roxburghii was applied to the supplementary food nutrient sprinkling agent,and the mixing uniformity of the supplementary food nutrient sprinkling a⁃gent and the stability of each nutrient in the acceleration process were investigated.The results showed that the inhibitory rate of Sophora japonica L.&Rosa roxburghii extract on hyaluronidase ac⁃tivity was 73%,and compared with the model group,the Sophora japonica L.&Rosa roxburghii ex⁃tract could significantly reduce ear swelling,spleen index,thymus index and licking times of mice,which proved that the Sophora japonica L.&Rosa roxburghii extract had better anti⁃allergic and an⁃tipruritic effects..RSD values of all nutrients in the composition of Sophora japonica L.&Rosa rox⁃burghii extract were less than 5%,and the attenuation of all nutrients was stable within 6 months of acceleration,which met the requirements of national standards.In this study,Sophora japonica L.&Rosa roxburghii extract has the anti⁃allergy and anti⁃itching effect,and predicts the decay of each nutrient in the supplement nutrient spray of this composition,providing certain data support and ref⁃erence for the development of anti⁃allergy and anti⁃itching supplement nutrient spray products.

关 键 词：槐米刺梨 抗过敏 止痒 辅食营养素撒剂 稳定性 

分 类 号：TS216[轻工技术与工程—粮食、油脂及植物蛋白工程]