Effect of nocturia in patients with different severity of obstructive sleep apnea on polysomnography: A retrospective observational study  

作　　者：Chin-Heng Lu Hung-Min Chang Kuang-Hsi Chang Yen-Chuan Ou Chao-Yu Hsu Min-Che Tung Frank Cheau-Feng Lin Stella Chin-Shaw Tsai 

机构地区：[1]Division of Urology,Department of Surgery,Tungs’Taichung Metroharbor Hospital,Taichung,Taiwan,China [2]Rong Hsing Research Center for Translational Medicine,Chung Hsing University,Taichung,Taiwan,China [3]College of Life Sciences,Chung Hsing University,Taichung,Taiwan,China [4]Department of Otolaryngology,Tungs’Taichung Metroharbor Hospital,Taichung,Taiwan,China [5]Department of Medical Research,Tungs’Taichung Metroharbor Hospital,Taichung,Taiwan,China [6]General Education Center,Jen-Teh Junior College of Medicine,Nursing and Management,Miaoli,Taiwan,China [7]Graduate Institute of Biomedical Sciences,China Medical University,Taichung,Taiwan,China [8]Department of Post-Baccalaureate Medicine,College of Medicine,Chung Hsing University,Taichung,Taiwan,China [9]Department of Nursing,Jen-Teh Junior College of Medicine,Nursing and Management,Miaoli,Taiwan,China [10]Department of Surgery,Chung Shan Medical University,Taichung,Taiwan,China [11]College of Medicine,Chung Shan Medical University,Taichung,Taiwan,China

出　　处：《Asian Journal of Urology》2024年第3期486-496,共11页亚洲泌尿外科杂志（英文）

基　　金：support from Tungs’Taichung Metroharbor Hospital(grant number#TTMHH-109R0048 to Stella Chin-Shaw Tsai).

摘　　要：Patients with suspected OSA were examined using PSG.They were divided into two groups based on the presence of nocturia.Nocturia was defined as a patient who needed to void at least once.Apneaehypopnea index(AHI)was employed to classify patients according to degrees of severity:AHI<5 events/h,5 events/hAHI<15 events/h,15 events/hAHI<30 events/h,and AHI30 events/h,defined as normal,mild OSA,moderate OSA,and severe OSA,respectively.Demographic variables,PSG parameters,International Prostate Symptom Scores(IPSSs),and quality of life scores due to urinary symptoms were analyzed.Results:In total 140 patients,114 patients had OSA(48 had mild OSA;34 had moderate OSA;and 32 had severe OSA)and 107 patients had nocturia.The total IPSS was significantly higher in nocturia patients in all groups except the group of severe OSA patients.With the increasing severity of OSA,more correlated factors related to nocturia were determined.In mild OSA patients,nocturia related to increased age(p=0.025),minimum arterial blood oxygenation saturation(p=0.046),and decreased AHI of non-rapid eye movement(p=0.047),AHI of total sleep time(p=0.010),and desaturation index(p=0.012).In moderate OSA patients,nocturia related to increased age(p<0.001),awake time(p=0.025),stage 1 sleep(p=0.033),and sleep latency(p=0.033),and decreased height(p=0.044),weight(p=0.025),and sleep efficiency(p=0.003).In severe OSA patients,nocturia related to increased weight(p=0.011),body mass index(p=0.009),awake time(p=0.008),stage 1 sleep(p=0.040),arousal number(p=0.030),arousal index(p=0.013),periodic limb movement number(p=0.013),and periodic limb movement index(p=0.004),and decreased baseline arterial blood oxygenation saturation(p=0.046).Conclusion:Our study revealed that there were more correlated factors related to nocturia with increasing severity of OSA.This study helps in clinical education and treatment for OSA patients with different severity.

关 键 词：NOCTURIA Obstructive sleep apnea POLYSOMNOGRAPHY Apnea-hypopnea index International Prostate Symptom Score 

分 类 号：R699[医药卫生—泌尿科学]