ILC3/IL-22在细菌性肺炎中的抗菌免疫研究进展  

Research Progress on Antibacterial Immunity of ILC3/IL-22 in Bacterial Pneumonia

作　　者：戴德嘉 李涵 黄璟昇 朱树馨 康伟超 何家康[1] 梁正敏[1] 彭建波 DAI Dejia;LI Han;HUANG Jingsheng;ZHU Shuxin;KANG Weichao;HE Jiakang;LIANG Zhengmin;PENG Jianbo(College of Animal Science and Technology,Guangxi University,Nanning 530005,China;College of Animal Science and Technology,Guangxi Vocational University of Agriculture,Nanning 530007,China)

机构地区：[1]广西大学动物科学技术学院,广西南宁530005 [2]广西农业职业技术大学动物科技学院,广西南宁530007

出　　处：《中国兽医杂志》2024年第9期102-109,共8页Chinese Journal of Veterinary Medicine

基　　金：广西重点研发项目(桂科AB23026082);广西科技基地和人才专项项目(桂科AD23026289);广西高校中青年教师科研能力提升项目(2022KY1211)。

摘　　要：Ⅲ型固有淋巴细胞(ILC3)是一种新型淋巴细胞,激活后通过产生白细胞介素-22(IL-22)和白细胞介素-17(IL-17)发挥抗菌和修复黏膜损伤的作用,本综述主要探讨ILC3/IL-22在细菌性肺炎中介导抗菌免疫的作用和机制,以期为细菌性肺炎的防控提供理论依据和研究思路。Group 3 innate lymphoid cells(ILC3) are a novel type of lymphoid cells,which playing an antibacterial and mucosal repair role by producing interleukin-22(IL-22) and interleukin-17(IL-17) after activation.This review explores the roles and mechanisms of ILC3/IL-22 in mediating antimicrobial immunity in bacterial pneumonia,aiming to provide theoretical basis and research perspectives for the prevention and control of bacterial pneumonia.

关 键 词：Ⅲ型固有淋巴细胞(ILC3) 白细胞介素-22(IL-22) 细菌性肺炎 抗菌免疫 

分 类 号：S852.4[农业科学—基础兽医学]