丙型肝炎患者焦虑和抑郁现状及其相关影响因素分析  

Analysis of anxiety and depression status and influencing factors in patients with hepatitis C

作　　者：虞接军 徐朋 刘鹏程[1] 杨丹丹 张琬悦[4] 陈玉妮[5] 张培栋 袁庆[1] 刘中夫 李健[1] YU Jie-jun;XU Peng;LIU Peng-cheng;YANG Dan-dan;ZHANG Wan-yue;CHEN Yu-ni;ZHANG Pei-dong;YUAN Qing;LIU Zhong-fu;LI Jian(Center for Disease Control and Prevention of Sexually Transmitted Diseases and AIDS,Chinese Center for Disease Control and Prevention,Beijing 102206,China;不详)

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]山东第一医科大学第一附属医院(山东省千佛山医院) [3]江苏省疾病预防控制中心 [4]云南省疾病预防控制中心 [5]文山壮族苗族自治州疾病预防控制中心 [6]徐州市疾病预防控制中心

出　　处：《现代预防医学》2024年第17期3207-3211,3230,共6页Modern Preventive Medicine

摘　　要：目的了解丙型肝炎(简称丙肝)患者焦虑和抑郁检出状况及相关因素,为改善该人群的心理健康提供依据。方法于2022年7—9月在云南省文山州和江苏省徐州市,使用综合医院焦虑/抑郁量表对486名丙肝患者进行了焦虑和抑郁状况问卷调查。采用χ2检验分析不同特征的丙肝患者焦虑和抑郁检出率的差异,采用多因素logistic回归模型分别分析丙肝患者焦虑和抑郁的相关因素。结果共收回有效问卷483份,问卷有效率为99.38%(483/486)。其中,焦虑症状检出率为22.15%(107/483),抑郁症状检出率31.88%(154/483)。多因素logistic回归模型结果显示,女性(OR=1.906,95%CI:1.165~3.120)、患有其他疾病(OR=2.957,95%CI:1.828~4.783)和有肝脏不适感(OR=3.360,95%CI:1.428~3.867)的患者焦虑风险更高;相比农民或民工,职业为无业或待业(OR=2.246,95%CI:1.264~3.992)的患者焦虑风险更高;相比家庭人均月收入>3000元,家庭人均月收入<1000元(OR=8.463,95%CI:2.432~29.452)和1000~3000元(OR=6.592,95%CI:1.899~22.882)的患者焦虑风险更高。年龄≥50岁(OR=1.972,95%CI:1.262~3.080)、患有其他疾病(OR=1.647,95%CI:1.082~2.507)和有肝脏不适感(OR=1.937,95%CI:1.220~3.074)的患者抑郁风险更高;相比家庭人均月收入>3000元,家庭人均月收入<1000元(OR=6.971,95%CI:3.011~16.139)和1000~3000元(OR=3.773,95%CI:1.607~8.857)的患者抑郁风险更高。结论丙肝患者中的焦虑和抑郁的比例较高,且与性别、年龄、职业、家庭人均月收入低、患有其他疾病和出现肝脏不适感有关,应采取相应的措施减少丙肝患者焦虑和抑郁的发生,以改善其心理健康。Objective To investigate the prevalence of anxiety and depression in patients with Hepatitis C(HCV)and its influencing factors,to provide basis for improving the mental health of this population.Methods From July to September 2022,a questionnaire survey on anxiety and depression was conducted among 486 HCV patients in Wenshan Prefecture of Yunnan Province and Xuzhou city of Jiangsu Province with the use of a comprehensive hospital anxiety/depression scale.The differences in the prevalence of anxiety and depression among HCV patients with different characteristics were analyzed using the Chi-square test,and a multivariate logistic regression model was used to analyze the influencing factors of anxiety and depression in HCV patients.Results A total of 483 valid questionnaires were collected,with an effective response rate of 99.38%(483/486).The detection rate of anxiety symptoms was 22.15%(107/483),and the detection rate of depression symptoms was 31.88%(154/483).The results of the multivariate logistic regression analysis indicated that females(OR=1.906,95%CI:1.165-3.120),patients with other diseases(OR=2.957,95%CI:1.828-4.783),and those experiencing liver discomfort(OR=3.360,95%CI:1.428-3.867)had a higher risk of anxiety.Compared to farmers or migrant workers,those who were unemployed or seeking employment(OR=2.246,95%CI:1.264-3.992)had a higher risk of anxiety.Individuals with per capita household monthly income less than 1000 yuan(OR=8.463,95%CI:2.432-29.452)or between 1000 and 3000 yuan(OR=6.592,95%CI:1.899-22.882)had a higher risk of anxiety compared to those with an income greater than 3000 yuan.For depression,individuals aged 50 years or older(OR=1.972,95%CI:1.262-3.080),those with other diseases(OR=1.647,95%CI:1.082-2.507),and those experiencing liver discomfort(OR=1.937,95%CI:1.220-3.074)had a higher risk.Individuals with a household per capita monthly income less than 1000 yuan(OR=6.971,95%CI:3.011-16.139)or between 1000 and 3000 yuan(OR=3.773,95%CI:1.607-8.857)had a higher risk of depression compared to

关 键 词：丙型肝炎 焦虑 抑郁 影响因素 

分 类 号：R512.63[医药卫生—内科学] R749.4[医药卫生—临床医学]