胆宁片预处理在糖尿病患者结肠镜检查前的应用效果分析  

Effectiveness analysis of Danning tablets in pre-treatment for colonoscopy in diabetes mellitus patients

作　　者：刘依秦 王超群 邱娇娜 LIU Yiqin;WANG Chaoqun;QIU Jiaona(Department of Endocrinology,First Affiliated Hospital,Naval Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学第一附属医院内分泌科,上海200433

出　　处：《药学实践与服务》2024年第9期407-410,共4页Journal of Pharmaceutical Practice and Service

基　　金：海军军医大学校级课题(2022QN058、2023YX005);老年长期照护教育部重点实验室(海军军医大学)。

摘　　要：目的探讨口服胆宁片在糖尿病患者结肠镜诊疗前肠道准备情况的应用效果。方法本研究选取了2022年11月至2024年5月期间,在我院内分泌科住院并接受结肠镜检查的100名2型糖尿病患者(年龄≥30岁)作为研究对象,随机分为①对照组(n=50),结肠镜检查前10 h服用68.56 g复方聚乙二醇电解质散,检查前6 h再次服用137.12 g复方聚乙二醇电解质散,②实验组(n=50),在对照组的肠道准备基础上,于检查前2 d连续口服胆宁片,每日3次,每次5片,采用波士顿量表(BBPS)评估两组患者肠道准备质量。结果实验组BBPS得分为(7.44±1.03),高于对照组BBPS得分(5.58±1.98),P<0.001,实验组肠道准备为优、良(BBPS评分≥6分)占96%,明显高于对照组的58%(P<0.001)。结论糖尿病患者行肠镜检查,在肠道准备前口服胆宁片能提高肠道清洁度,显著改善患者的肠道准备质量。Objective To investigate the efficacy of oral Danning tablets for bowel preparation for colonoscopy in diabetes mellitus patients.Methods A study was conducted from November 2022 to May 2024,100 type 2 diabetic patients(aged≥30 years)admitted to endocrinology department in our hospital were selected and scheduled for colonoscopy as research subjects.These patients were randomly divided into two groups:①A control group(n=50),received 68.56 g of polyethylene glycol electrolyte powder 10 hours before the colonoscopy and an additional 137.12 g six hours before the procedure.②An experimental group(n=50),in addition to the bowel preparation regimen of the control group,orally took Danning tablets three times daily,five tablets each time,starting two days before the colonoscopy.Results The experimental group had a BBPS score of(7.44±1.03),which was higher than the control group’s BBPS score of(5.58±1.98),P<0.001.In the experimental group,96%of the bowel preparations were rated as excellent or good(BBPS score≥6),significantly higher than the 58%in the control group(P<0.001).Conclusion In diabetic patients undergoing colonoscopy,oral administration of Danning tablets during bowel preparation could improve bowel cleanliness and significantly enhance the quality of bowel preparation.

关 键 词：胆宁片 糖尿病 肠道准备 

分 类 号：R587.1[医药卫生—内分泌]