硝基取代苯酰基硫脲配合物的合成及其生物活性研究  

Synthesis of Nitro-substituted Benzoyl Thiourea Complex and its Bioactivity

作　　者：李倩 刘焰其 李雨菲 王月瑶 童翔 杨雨茹 姜敏[1] LI Qian;LIU Yanqi;LI Yufei;WANG Yueyao;TONG Xiang;YANG Yuru;JIANG Min(Shaanxi Key Laboratory of Catalysis,School of Chemical and Environmental Sciences,Shaanxi University of Technology,Hanzhong 723000,China)

机构地区：[1]陕西省催化基础与应用重点实验室陕西理工大学化学与环境科学学院,陕西汉中723000

出　　处：《化工技术与开发》2024年第9期8-13,共6页Technology & Development of Chemical Industry

基　　金：陕西理工大学大学生创新创业训练项目(202210720014);陕西省科技厅自然科学基金项目(2022JM-133);陕西省教育厅重点实验室项目(21JS001)。

摘　　要：绿色高效的植物生长调节剂的研发是目前农药学的热点工作。本研究将间硝基苯甲酰氯、硫氰酸铵与对氨基苯甲酸反应,一锅法合成了N-(3-硝基苯甲酰基)-N'-(3-羧基苯基)硫脲(记为Th1),并与稀土盐SmCl_(3)·6H_(2)O进行配位,合成了相应的Sm配合物。采用紫外光谱、红外光谱、荧光分析等手段,对Th1及其配合物进行了初步表征,采用平皿法探究了其生长调节性能。实验结果表明,配合物中的荧光源自配位后Sm原子的激发;测试浓度范围内的硫脲体系,对小麦的生长调控呈现低浓度促进、高浓度抑制的态势;转光膜条件下,配合物和Th1均能促进小麦叶片中叶绿素含量的增加,对小麦的根活力有较大的提升。In this study,N-(3-nitrobenzoyl)-N'-(3-carboxyphenyl)thiourea(denoted as Th1)was synthesized by one-pot reaction of m-nitrobenzoyl chloride,ammonium thiocyanate and m-aminobenzoic acid,and coordinated with the rare earth salt SmCl_(3)·6H_(2)O to synthesize the corresponding Sm complex.Th1 and its complex were preliminarily characterized by ultraviolet spectroscopy,infrared spectroscopy,fluorescence analysis,its growth regulation performance was explored by flat dish method.The results showed that the fluorescence in the complex was generated by the excitation of Sm atoms after the coordination.Thiourea system promoted wheat growth at low concentration and inhibited it at high concentration.Both the complex and Th1 could promote the increase of chlorophyll content in wheat leaves and the root activity in wheat under the condition of photofilm.

关 键 词：硫脲衍生物 稀土配合物 合成 生物活性 

分 类 号：TQ452[化学工程—农药化工]