化疗所致周围神经病变评估与非药物管理的最佳证据总结  

Best evidence summary about assessment and non-pharmacological management of chemotherapy-induced peripheral neuropathy

作　　者：魏金梅[1] 李亚楠 刘磊[2] 李新省[3] 靳英辉 梁军利[5] Wei Jinmei;Li Yanan;Liu Lei;Li Xinsheng;Jin Yinghui;Liang Junli(Department of Gastroenterology,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China;Breast Center,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China;Department of Hepatobiliary Surgery,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China;The Center for Evidence-Based and Translational Medicine of Zhongnan Hospital of the University,Wuhan 430071,China;Nursing Department,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第四医院消化内科,石家庄050000 [2]河北医科大学第四医院乳腺中心,石家庄050000 [3]河北医科大学第四医院肝胆外科,石家庄050000 [4]武汉大学中南医院循证与转化医学中心,武汉430071 [5]河北医科大学第四医院护理部,石家庄050000

出　　处：《中国实用护理杂志》2024年第25期1977-1985,共9页Chinese Journal of Practical Nursing

基　　金：河北省卫生健康委科研基金项目(20190715)。

摘　　要：目的检索、总结化疗所致周围神经病变评估与非药物管理的最佳证据。方法系统检索国内外临床决策支持系统、指南网、数据库及相关学会网站中与化疗所致周围神经病变评估与非药物管理的相关的文献, 检索时限为2018年1月1日至2023年12月4日, 文献类型包括临床决策、指南、专家共识、证据总结、系统评价、随机对照研究。由4名研究者对纳入文献进行质量评价和证据提取。结果共纳入18篇文献, 其中临床决策1篇, 指南2篇、专家共识3篇、证据总结5篇, 系统评价4篇, 随机对照研究3篇。从评估、运动疗法、针灸疗法、冷冻疗法、加压疗法、健康教育、多学科协作7个项目, 总结了21条证据。结论非药物干预是改善化疗所致周围神经病变的有效手段。医务人员应结合专业判断与患者意愿, 审慎、明确、明智的使用最佳证据, 以预防或减轻化疗所致周围神经病变, 从而提高患者的生命质量。Objective To retrieve,evaluate and summarize the best evidence for the assessment and non-pharmacological management of chemotherapy-induced peripheral neuropathy.Methods The literature related to the assessment and non-pharmacological management of chemotherapy-induced peripheral neuropathy was systematically searched from January 1,2018 to December 4,2023 in clinical decision support systems,guideline networks,databases and related society websites at home and abroad,including clinical decision-making,guidelines,expert consensus,evidence summary,systematic review,and randomized controlled studies.Four reviewers evaluated the quality of the included studies and extracted evidence.Results A total of 18 articles were included,including 1 clinical decision,2 guidelines,3 expert consensuses,5 evidence summaries,4 systematic reviews,and 3 randomized controlled studies.A total of 21 pieces of evidence were summarized from 7 items:assessment,exercise therapy,acupuncture therapy,cryotherapy,compression therapy,health education,and multidisciplinary diagnosis and treatment.Conclusions Non-pharmacological intervention is an effective means to improve chemotherapy-induced peripheral neuropathy.Medical personnel should combine professional judgment with patient′s will,prudently,wisely and clearly use the best evidence to prevent or reduce chemotherapy-induced peripheral neuropathy and improve patients′quality of life.

关 键 词：化学疗法 周围神经病变 评估 非药物管理 肿瘤 循证护理学 

分 类 号：R473.73[医药卫生—护理学]