获得性反应性穿通性胶原病皮肤镜下特征  

作　　者：李胜华 严悦梅 王晓杰 张庆江 陈祥义 殷文浩 

机构地区：[1]浙江省嘉兴市第一医院,314000

出　　处：《浙江临床医学》2024年第8期1175-1176,1179,共3页Zhejiang Clinical Medical Journal

基　　金：嘉兴市中医药重点学科建设计划(2019XK-C06)。

摘　　要：目的探讨获得性反应性穿通性胶原病(ARPC)皮肤镜下特征以明确皮肤镜在其辅助诊断中的应用价值。方法回顾性分析2021年9月至2023年4月经组织病理确诊的11例获得性反应性穿通性胶原病患者的临床资料,分析70余处皮损的皮肤镜特征。结果获得性反应性穿通性胶原病皮肤镜下可分为3种模式:模式1中央肥厚黄红色到黄棕色无结构区,周缘裂隙,外围红斑、白色鳞屑,可见无结构区及放射状、线状、环形、发卡状血管;模式2中央黄红色无结构区,点球状出血,白色鳞屑,周缘粉红色、白色无结构区,外围放射状棕色网状线包围;模式3中央多色无结构区域,包括黄红色、红色、棕色和白色区域,外围放射状棕色网状线包围。模式1有临床意义,为皮肤活检首选,且同一患者中存在一种以上模式。结论获得性反应性穿通性胶原病在皮肤镜下具有特征性表现,在辅助诊断中具有应用价值。Objective To describe the dermoscopic features of acquired reactive perforating collagenosis(ARPC)and to explore the application value of dermoscopy in assisting the diagnosis of ARPC.Methods Eleven patients with ARPC were collected from Department of Dermatology,the first hospital of jiaxing between September 2021 and April 2023.A total of more than 70 skin lesions from 11 ARPC patients were subjected to dermoscopy,and their dermoscopic features were analyzed.Results ARPC patients were divided into three patterns underage the dermoscopic characteristics.The pattern 1 was composed of a central red-brown or yellow-brown structureless area,Peripheral fissures,a peripheral pinkish structureless area and radial,linear,circular and hairpin vessels.The pattern 2 was composed of a central yellow-to-pink unstructured area and blood spots,a peripheral pinkish and/or structureless area,surrounded by brown reticular lines.The pattern 3 was composed of central multicolor structureless areas including red,brown and white areas,surrounded by brown reticular lines.Among them,pattern 1 had clinical significance and was the first choice for skin biopsy,and there was more than one lesions in the same patient.Conclusion Dermoscopy has good application value in assisting the diagnosis of ARPC.

关 键 词：获得性反应性穿通性胶原病 皮肤镜 诊断 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]