中性粒细胞-淋巴细胞比值或可帮助术前预判急性阴囊疼痛患儿是否发生睾丸扭转  

Neutrophil-to-lymphocyte ratio may help predict pediatric testicular torsion in chlidren with acute scrotal pain before surgery

作　　者：贺显雅 王晨 杨勇军 陈俊杰 伍学成 李卓[1] 刘哲[1] 宋光庆 滕伊漓 陈佳[1] 王洪卫 郑华义 李远伟[1] 卢强[1,2] HE Xianya;WANG Chen;YANG Yongjun;CHEN Junjie;WU Xuecheng;LI Zhuo;LIU Zhe;SONG Guangqing;TENG Yili;CHEN Jia;WANG Hongwei;ZHENG Huayi;LI Yuanwei;LU Qiang(Department of Urology,Hunan Provincial People's Hospital,The First Affiliated Hospital of Hunan Normal University,Changsha 410007;Department of General Surgery and Urology,Hongjiang People's Hospital,Hongjiang 420078,China)

机构地区：[1]湖南省人民医院,湖南师范大学附属第一医院泌尿外科,湖南长沙410007 [2]洪江市人民医院普外泌外科,湖南洪江420078

出　　处：《现代泌尿外科杂志》2024年第9期785-789,共5页Journal of Modern Urology

基　　金：湖南省普惠性政策与创新环境建设计划-临床医疗技术创新引导项目(No.2020SK50902);国家科技部重点研发计划重点专项子项目(No.2021YFC2009300)。

摘　　要：目的探讨应用中性粒细胞-淋巴细胞比值(NLR)预判急性阴囊疼痛患儿睾丸扭转(TT)的准确性。方法回顾性收集2017年1月—2024年1月于湖南省人民医院和洪江市人民医院接受住院治疗的158例术前超声诊断疑似为TT的患儿资料,所有患儿均急诊接受了睾丸探查手术。根据探查结果分为TT组(143例)和非TT组(15例)。分析两组患儿的临床资料、实验室检查和彩超检查结果,采用受试者工作特征(ROC)曲线分析NLR对TT诊断的敏感度和特异度。结果TT组和非TT组临床资料差异无统计学意义(P>0.05)。TT组NLR明显高于非TT组[(4.82±2.37)vs.(2.85±0.75),P<0.05]。NLR预测TT的最佳截断值为2.07,ROC曲线下面积(AUC)为0.809(95%CI:0.709~0.909),敏感度和特异度分别为97.9%、93.3%,显著高于其他因素。结论对于超声诊断疑似TT的急性阴囊疼痛患儿,NLR或可帮助预判是否发生TT,作为此类患儿临床治疗决策的重要参考指标。Objective To explore the feasibility and accuracy of neutrophil-to-lymphocyte ratio(NLR)in the prediction of testicular torsion(TT)in children with acute scrotal pain.Methods A retrospective case-control study was performed on 158 pediatric patients with ultrasound suspicion of TT who underwent surgical testicular examination during Jan.2017 and Jan.2024.The patients were divided into TT group and non-TT group.Clinical data and laboratory data at admission were analyzed.Sensitivity and specificity of NLR to TT were determined with the area under the curve(AUC)represented on the receiver operating characteristic(ROC)curves.Results There were with no statistically significant differences in clinical data between the two groups(P>0.05).The NLR was significantly higher in the TT group than in the non-TT group[(4.82±2.37)vs.(2.85±0.75),P<0.05].The optimal cut-off value of TT predicted by NLR was 2.07,the AUC was 0.809(95%CI:0.709-0.909),and the sensitivity and specificity were 97.9%and 93.3%,respectively,which were significantly higher than other factors.Conclusion For suspicious ultrasound diagnosis of pediatric acute scrotal pain cases,NLR can be used to predict the possibility of TT and may help to evaluate the urgent surgical treatment in these patients.

关 键 词：睾丸扭转 中性粒细胞-淋巴细胞比值 儿童 睾丸附睾炎 

分 类 号：R726.9[医药卫生—儿科]