不同材料用于额颞部大面积颅骨缺损修复的临床疗效分析  

Clinical efficacy analysis of different materials for the repair of large frontal and temporal skull defects

作　　者：廖晋 才智 李宇 雷晋 赵恺[1] 牛洪泉[1] 舒凯[1] 雷霆[1] LIAO Jin;CAI Zhi;LI Yu;LEI Jin;ZHAO Kai;NIU Hongquan;SHU Kai;LEI Ting(Department of Neurosurgery,Tongji Hospital,Tongji Medical College,Huazhong Universty of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院神经外科,武汉430030

出　　处：《临床外科杂志》2024年第8期811-813,共3页Journal of Clinical Surgery

基　　金：湖北省病理生理学会面上项目(2021HBAP007);武汉市东湖新技术开发区第十一批“3551光谷人才计划”;同济医院横向课题(2022125)。

摘　　要：目的探究钛网和聚醚醚酮用于额颞部大面积颅骨缺损修复的临床疗效。方法2018年4月~2022年6月因额颞部大面积颅骨缺损行颅骨修复的病人150例,按修复材料不同分为钛网组(96例)和聚醚醚酮组(54例),比较两组术后手术部位感染、出血、皮下积液、癫痫发作、植入物断裂或外露等。结果聚醚醚酮组96.3%病人修补材料需置入颞肌下,高于钛网组的78.1%,两组比较差异有统计学意义(P<0.05)。两组术后并发症包括感染、出血、术后新发癫痫、植入物断裂或外漏等情况比较差异均无统计学意义(P>0.05),但聚醚醚酮组病人术后皮下积液发生率高于钛网组(14.8%VS 4.2%),差异有统计学意义(P<0.05)。结论钛网和聚醚醚酮材料均可用于额颞部大面积颅骨缺损修复手术,聚醚醚酮材料在颅骨修复术中易合并术区皮下积液。Objective To investigate the clinical outcomes of cranioplasty with polyether ether ketone(PEEK)or titanium after large craniectomy in patients.Methods Clinical data of 150 patients undergoing skull repair due to large frontotemporal skull defect in our hospital from April 2018 to June 2022 were retrospectively analyzed,and they were divided into titanium mesh group and PEEK group according to different repair materials.The conditions of surgical site infection,bleeding,subcutaneous effusion,seizure,implant rupture or exposure in the two groups were compared.Results In the PEEK group,96.3%of patients needed to implant the repair material under the temporal muscle,which was significantly higher than that in the titanium mesh group(78.1%)(P<0.05).There were no significant differences in postoperative complications including infection,bleeding,seizure,implant rupture or leakage between the two groups(P>0.05).However,the incidence of postoperative subcutaneous effusion in PEEK group was higher than that in titanium mesh group(14.8%VS 4.2%,P<0.05),and the difference was statistically significant.Conclusion Both titanium and PEEK can be used in cranioplasty for patients with large frontotemporal cranial defects.Subcutaneous effusion is common in patients underwent cranioplasty with PEEK postoperatively,which needs to be paid more attention.

关 键 词：大面积颅骨缺损 颅骨修复 钛网 聚醚醚酮 皮下积液 

分 类 号：R651.1[医药卫生—外科学]