桑椹化学成分与药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Mori Fructus

作　　者：韩非若 李婷 阿力亚·麦麦提敏 张仲瑞 艾柯代·艾地汗 徐伟 龚普阳 HAN Feiruo;LI Ting;ALIYA Mamitimin;ZHANG Zhongrui;AKIDA Adiham;XU Wei;GONG Puyang(College of Pharmacy,Southwest Minzu University,Chengdu 610041,China;Department of Traditional Chinese Medicine,Maternity and Child Health Care of Zaozhuang,Zaozhuang 277000,China)

机构地区：[1]西南民族大学药学院,四川成都610041 [2]枣庄市妇幼保健院中医科,山东枣庄277000

出　　处：《中草药》2024年第15期5274-5285,共12页Chinese Traditional and Herbal Drugs

基　　金：西南民族大学中央高校基本科研业务费专项(ZYN2024035);西南民族大学大学生创新创业训练计划项目(202310656009)。

摘　　要：桑椹Mori Fructus是使用历史悠久的药食两用中药,有滋阴补血及生津润燥之功效。现代研究表明桑椹主要含有黄酮、酚酸、生物碱、苯丙素、苯并呋喃、萜类及多糖等化学成分。药理学研究证实其主要具有调血脂、抗糖尿病、保肝、抗氧化、抗衰老、神经保护、免疫调节、抗炎、抗肿瘤、骨保护及抗便秘等作用。通过对近年来国内外关于桑椹化学成分和药理作用研究报道进行总结,为桑椹药用价值的深入挖掘和相关产品的开发提供参考。Sangshen(Mori Fructus)is an edible and medicinal homologous traditional Chinese medicine with a long history of use.It has the efficacies of nourishing yin,tonifying blood,generating fluids and moistening dryness.Modern phytochemical studies have shown that Mori Fructus mainly contains flavonoids,phenolic acids,alkaloids,phenylpropanoids,benzofurans,terpenoids and polysaccharides,etc.Pharmacological studies have shown that it mainly possesses the biological activities of regulating blood lipids,anti-diabetes,liver protection,anti-oxidation,anti-aging,neuroprotection,immune regulation,anti-inflammation,antitumor,bone protection and anti-constipation,etc.This paper summarizes the research reports on the chemical constituents and pharmacological effects of Mori Fructus,in order to provide reference for the in-depth excavation of the medicinal value and the development of related products of Mori Fructus.

关 键 词：桑椹 多酚 多糖 保肝 调血脂 抗糖尿病 抗动脉粥样硬化 神经保护 

分 类 号：R285[医药卫生—中药学]