左束支起搏治疗心力衰竭的应用现状  

Aapplication of left bundle branch pacing in the treatment of heart failure

作　　者：张宁 刘现亮 Zhang Ning;Liu Xianliang(Department of Cardiology,Yantai Affiliated Hospital of Binzhou Medical College,Yantai,Shandong 264100,China;Department of Cardiology,Jinan Central Hospital,Jinan,Shandong 250013,China)

机构地区：[1]滨州医学院烟台附属医院心内科,山东烟台264100 [2]济南市中心医院心内二科,山东济南250013

出　　处：《医药前沿》2024年第27期48-51,共4页Journal of Frontiers of Medicine

摘　　要：传统的右心室心尖部或室间隔起搏方式属于非生理性起搏,可能导致心脏收缩失同步,从而引发心力衰竭或心房颤动。相比之下,希氏束-浦肯野纤维系统起搏被认为是一种更为生理的起搏方式。然而,随着对希氏束起搏(HBP)的研究深入,发现其存在起搏阈值高、导线易脱落、手术难度大以及推广受限等缺点,限制了其应用。近年来,左束支起搏作为一种新兴的治疗方式,应用越来越广泛,特别是在心力衰竭患者中,已成为研究的热点。本文就左束支起搏在心力衰竭患者中的临床应用现状进行综述,以期为解决心力衰竭问题提供新的思路。Traditional right ventricular apex or interventricular septum pacing is considered non-physiological,which may lead to cardiac dyssynchrony and potentially result in heart failure or atrial fibrillation.In contrast,His Purkinje conduction system pacing is regarded as a more physiological pacing method.However,as research on His bundle pacing(HBP)has advanced,several limitations have been identified,including high pacing thresholds,lead dislodgement,surgical complexity,and limited adoption,which restrict its application.In recent years,left bundle branch pacing has emerged as a novel therapeutic approach and is being increasingly used,particularly in patients with heart failure,making it a focus of current research.This article reviews the current clinical application of left bundle branch pacing in patients with heart failure,aiming to provide new insights for addressing heart failure issues.

关 键 词：综述 心力衰竭 心血管病学 左束支起搏 心脏再同步化治疗 

分 类 号：R541[医药卫生—心血管疾病]