双酰胺类化合物引入环丙基制备新型杀虫剂的研究  

Study on Novel Pesticides by Introducing Cyclopropyl Group into Diamide Compounds

作　　者：高鹏[1] 唐余 陈诗桦 潘彤[1] GAO Peng;TANG Yu;CHEN Shi-hua;PAN Tong(College of Chemistry and Chemical Engineering,Changsha University of Science and Technology,Changsha 410000,China)

机构地区：[1]长沙理工大学化学化工学院,湖南长沙410000

出　　处：《精细化工中间体》2024年第4期10-12,16,共4页Fine Chemical Intermediates

摘　　要：在双酰胺类化合物中引入环丙基的结构改造,旨在通过结构改造,提升双酰胺类杀虫剂的杀虫广谱。以2-氟-3-胺基苯甲酸甲酯为原料制备新型双酰胺类化合物N-[2-溴-4-(1,1,1,2,3,3,3-七氟丙-2-基)-6-三氟甲氧基苯基]-3-[N-(环丙甲基)苯甲酰胺基]-2-氟苯甲酰胺(BCPF)。有利于该化合物进一步杀虫药效、作用机制及高效杀虫剂的研究。Structural modification of bisamide compounds by introducing cyclopropyl group to improve the insecticidal broad spectrum and mechanism was studied.A novel biamide compound N-[2-bromo-4-(1,1,1,2,3,3,3-heptafluoropropyl-2-yl)-6-trifluoromethoxy-phenyl]-3-[N-(cyclopropyl methyl)benzoyl]-2-fluorobenzamide(BCPF)was prepared from 2-fluoro-3-amino methyl benzoate as raw material.It is beneficial to further study on the efficacy and mechanism of the compound and the development of efficient pesticides.

关 键 词：环丙基双酰胺类化合物 2-氟-3-胺基苯甲酸甲酯 2-氟-3-[N-(环丙甲基)苯甲酰胺]苯甲酸 N-[2-溴-4-(1 1 1 2 3 3 3-七氟丙-2-基)-6-三氟甲氧基苯基]-3-[N-(环丙甲基)苯甲酰胺基]-2-氟苯甲酰胺 

分 类 号：TQ453.2[化学工程—农药化工]