赣州地区成人带状疱疹发病现状及关联因素分析  

Analysis of the current situation and associated factors of adult herpes zoster in Ganzhou area

作　　者：尹平英 傅琳 邓志强 Yin Ping-ying;Fu Lin;Deng Zhi-qiang(,Vaccination Clinic,Shangyou Center for Disease Control and Prevention,Ganzhou 341200,Jiangxi,China;Department of Disease Control,Shangyou Center for Disease Control and Prevention,Ganzhou 341200,Jiangxi,China;Department of Immunization Planning,Shangyou Center for Disease Control and Prevention,Ganzhou 341200,Jiangxi,China)

机构地区：[1]江西省上犹县疾病预防控制中心预防接种门诊,江西赣州341200 [2]江西省上犹县疾病预防控制中心疾病控制科,江西赣州341200 [3]江西省上犹县疾病预防控制中心免疫规划科,江西赣州341200

出　　处：《四川生理科学杂志》2024年第9期1905-1907,1967,共4页

基　　金：赣州市科技计划项目(编号:GZ2023ZSF588)。

摘　　要：目的:探讨赣州地区成人带状疱疹发病现状并对其关联因素进行分析。方法:选取2022年1月至2023年12月于江西省上犹县人民医院就诊的150例带状疱疹患者作为研究对象的带状疱疹组,另选取同期于江西省上犹县人民医院体检科进行健康检查的150名正常健康人作为研究对象的健康组。比较所有受试者一般资料,包括性别、年龄、民族、机械性创伤、系统性疾病(如糖尿病史、肾脏病、发热、高血压等)、合并肿瘤情况、带状疱疹患者接触史、疫苗接种史、近期精神压力大/劳累、近3m内使用免疫抑制剂及皮质类固醇激素情况等,Logistic回归分析赣州地区成人带状疱疹发病的关联因素。结果:本院150例带状疱疹患者临床症状主要表现为低热、上感和神经痛(多为剧烈疼痛)。带状疱疹组和健康组受试者间性别、民族、带状疱疹接触史和近期精神压力大/劳累发生情况无明显差异(P>0.05)。带状疱疹组中年龄较健康组高、机械性创伤史、糖尿病史、肾脏病、发热、高血压、合并肿瘤史、疫苗接种史和使用免疫抑制剂/皮质类固醇激素情况(近3m)较健康组多(P<0.05)。Logistic回归分析显示:机械性创伤史、糖尿病史、疫苗接种史和使用免疫抑制剂/皮质类固醇激素(近3m)是带状疱疹发病相关危险因素(P<0.05)。结论:机械性创伤史、糖尿病史、疫苗接种史和使用免疫抑制剂/皮质类固醇激素(近3m)是带状疱疹发病相关危险因素,临床可据此为居民预防和控制带状疱疹制定科学策略。Objective:To explore the current situation of adult herpes zoster in Ganzhou area and analyze its associated factors.Methods:A total of 150 patients with herpes zoster treated in Shangyou County People's Hospital,Jiangxi,and 150 healthy controls who underwent health examination in physical examination department of Shangyou County People's Hospital were enrolled as herpes zoster group and healthy group between January 2022 and December 2023,respectively.The general data of all subjects were compared,including gender,age,nationality,mechanical trauma,systemic diseases(such as history of diabetes,kidney disease,fever,hypertension,etc.),combined tumors,contact history of herpes zoster patients,vaccination history,recent mental stress/fatigue,use of immunosuppressants and corticosteroids in the past three months,etc.Logistic regression analysis was conducted to analyze the associated factors of adult herpes zoster in Ganzhou.Results:In the 150 patients with herpes zoster,main clinical symptoms were as follows:low-grade fever,upper sensation and neuralgia(mainly on severe pain).There was no significant difference in gender,nationality,contact history of herpes zoster or recent heavy mental stress/fatigue between herpes zoster group and healthy group(P>0.05).The age of patients in herpes zoster group was older than that in healthy group,and proportions of mechanical trauma history,diabetes mellitus history,kidney disease,fever,hypertension,tumor history,vaccination history and use of immunosuppressants/corticosteroids(in the last 3 months)were higher than those in healthy group(P<0.05).Logistic regression analysis showed that history of mechanical trauma,history of diabetes mellitus,vaccination history and use of immunosuppressants/corticosteroids(in the last 3 months)were risk factors of herpes zoster onset(P<0.05).Conclusion:History of mechanical trauma,history of diabetes,history of vaccination and use of immunosuppressants/corticosteroids(nearly 3 months)are risk factors related to the onset of herpes zoster,which

关 键 词：成人 带状疱疹 发病率 危险因素 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]