煤工尘肺患者的结核潜伏感染风险及危险因素分析  

Analysis of the risk and risk factors of latent tuberculosis infection in coal worker pneumoconiosis patients

作　　者：肖泽蕾 陈峭 Xiao Ze-lei;Chen Qi(Ganzhou Economic and Technological Development Zone Disease Prevention and Control Center,Ganzhou 341000,Jiangxi,China;Ganzhou Fifth People's Hospital,Ganzhou 341000,Jiangxi,China)

机构地区：[1]赣州经济技术开发区疾病预防控制中心,江西赣州341000 [2]赣州市第五人民医院感染科,江西赣州341000

出　　处：《四川生理科学杂志》2024年第9期1930-1932,1977,共4页

摘　　要：目的:分析煤工尘肺结核潜伏感染风险及危险因素。方法:选取2020年1月至2023年7月赣州市第五人民医院救治的煤工尘肺患者80例,采用X线胸片和干扰素释放试验(QuantiFERON-TB GOLD,QFT)筛查结核潜伏感染情况,通过病历档案收集患者临床资料,采用Logistic回归模型分析此类患者结核潜伏感染的危险因素。结果:80例煤工尘肺患者结核潜伏感染率为63.75%,划作结核潜伏感染组、无结核潜伏感染组分别有51例和29例。两组在工种、工作场所通风情况和吸烟频率的比较差异有统计学意义(P<0.05);但在年龄、文化程度、婚姻状况等其他资料比较,差异无统计学意义。Logistic回归模型结果显示,混合工种、工作场所通风情况差是煤工尘肺结核潜伏感染的独立危险因素(P<0.05)。结论:煤工尘肺结核潜伏感染风险较高,混合工种、工作场所通风情况差是煤工尘肺结核潜伏感染的独立危险因素,应加强煤工尘肺患者结核预防意识,降低感染风险。Objective:To analyze the risk and risk factors of latent tuberculosis infection in coal worker pneumoconiosis patients.Methods:Eighty coal worker pneumoconiosis patients treated in Ganzhou Fifth People's Hospital from January 2020 to July 2023 were selected.X-ray chest films and QuantiFERON-TB GOLD(QFT)were used to screen for latent tuberculosis infection.Clinical data of patients were collected through medical records,and logistic regression models were used to analyze the risk factors for latent tuberculosis infection.Results:The latent infection rate of tuberculosis in 80 coal worker pneumoconiosis patients was 63.75%.There were 51 cases in the latent infection group and 29 cases in the non-latent infection group,respectively.There was a statistically significant difference between the two groups in terms of job type,workplace ventilation,and smoking frequency(P<0.05);However,compared with other data such as age,education level,and marital status,there was no statistically significant difference.The results of the logistic regression model showed that mixed occupations and poor ventilation in the workplace were independent risk factors for latent tuberculosis infection of coal worker pneumoconiosis(P<0.05).Conclusion:The risk of latent tuberculosis infection of coal worker pneumoconiosis is quite high;and mixed occupations and poor ventilation in the workplace are independent risk factors for latent tuberculosis infection of coal worker pneumoconiosis.It is necessary to strengthen the awareness of tuberculosis prevention in coal worker pneumoconiosis patients and reduce the risk of infection.

关 键 词：煤工尘肺 结核潜伏感染 感染现况 危险因素 

分 类 号：R135.2[医药卫生—劳动卫生]