生血宝联合琥珀酸亚铁治疗产褥期缺铁性贫血对外周血RBC、Mcv、Sf水平的影响  

Effect of Shengxuebao combined with ferrous succinate in the treatment of postpartum iron deficiency anemia on peripheral blood RBC,Mcv,and Sf levels

作　　者：柯文敏 Ke Wen-min(Department of Obstetrics and Gynecology,Duchang Maternal and Child Health Hospital,Jiujiang 332000,Jiangxi,China)

机构地区：[1]都昌县妇幼保健院妇产科,江西九江332000

出　　处：《四川生理科学杂志》2024年第9期2101-2103,共3页

摘　　要：目的:探讨生血宝联合琥珀酸亚铁治疗产褥期缺铁性贫血对外周血红细胞计数(Red blood cell count,RBC)、平均红细胞体积(Mean corpuscular volume,Mcv)、血清铁蛋白(Serum ferritin,Sf)水平的影响。方法:选择2020年3月~2023年12月本院收治的60例产褥期缺铁性贫血产妇作为研究对象,按随机数字表法分为对照组和观察组,各30例。对照组接受琥珀酸亚铁治疗,观察组接受琥珀酸亚铁联合生血宝治疗。比较治疗前、治疗1m后两组血液指标[RBC、Mcv、平均红细胞血红蛋白含量(Mean corpuscular hemoglobin,MCH)]、铁代谢指标[Sf、转铁蛋白受体(Soluble transferrin receptor,STFR)、转铁蛋白饱和度(Transferin saturation,TSAT)]的变化情况,并比较两组疗效和治疗期间不良反应发生率。结果:观察组治疗有效率明显高于对照组(P<0.05);治疗后,观察组RBC、MCV、MCH、Sf、TSAT水平明显高于对照组(P<0.05),STFR水平明显低于对照组(P<0.05);两组不良反应发生率无明显差异(P>0.05)。结论:生血宝联合琥珀酸亚铁可改善产褥期缺铁性贫血患者血液学指标,提高红细胞的发育程度,改善铁代谢水平。Objective:To explore the effects of Shengxuebao combined with ferrous succinate in the treatment of postpartum iron deficiency anemia on peripheral blood red blood cell count(RBC),mean red blood cell volume(Mcv),and serum ferritin(Sf)levels.Methods:Sixty postpartum pregnant women admitted to our hospital from March 2020 to December 2023 were selected as the research subjects.They were randomly divided into a control group and an observation group using a random number table method,with 30 cases in each group.The control group received treatment with ferrous succinate,while the observation group received treatment with ferrous succinate combined with Shengxuebao.Compare the changes in blood indicators[RBC,Mcv,mean corpuscular hemoglobin content(MCH)],iron metabolism indicators[Sf,transferrin receptor(STFR),transferrin saturation(TSAT)]between the two groups before and one month after treatment,and compare the incidence of adverse reactions during the treatment period between the two groups.Results:After treatment,the levels of RBC,MCV,and MCH in the observation group were higher than those in the control group(P<0.05);After treatment,the Sf and TSAT levels in the observation group were higher than those in the control group,while the STFR levels were lower than those in the control group(P<0.05);There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of Shengxuebao and ferrous succinate can improve hematological indicators,enhance the development of red blood cells,and improve iron metabolism levels in postpartum iron deficiency anemia patients.

关 键 词：产褥期 缺铁性贫血 生血宝 琥珀酸亚铁 影响 

分 类 号：R556.3[医药卫生—血液循环系统疾病] R446.11[医药卫生—内科学]