基于虚拟现实技术记忆相关训练的脑功能激活变化研究  

Changes of brain function activation based on VR memory-related training:a functional near infrared spectroscopy study

作　　者：罗红 徐丽 Luo Hong;Xu Li(Department of Rehabilitation Medicine,Sichuan Academy of Medical Sciences,Sichuan Provincial People’s Hospital,Chengdu 610072,China)

机构地区：[1]四川省医学科学院.四川省人民医院康复科,成都610072

出　　处：《中国康复》2024年第9期525-529,共5页Chinese Journal of Rehabilitation

基　　金：四川省科技部重点研发课题(2020YFS0415);四川省干部保健科研项目(川干研2022-201);四川省卫健委普及应用课题(21PJ079)。

摘　　要：目的:通过功能性近红外光谱技术(fNIRS)观察多模块3D-虚拟现实技术(VR)记忆相关训练对大脑功能激活状态的影响。方法:本研究共招募26例健康受试者,每人进行一次15min的多模块3D-VR记忆相关训练,26例受试者在训练前后分别接受53通道静息态fNIRS功能成像设备监测10min,对2次测试中所有通道采集到的额叶血氧信号及额叶功能评价指标HbO血氧浓度beat值及血氧信号均值进行对比,分析额叶功能变化及对皮层激活的影响。结果:与训练前比较,Oxy-Hb beta值在通道14、22、24、43有显著下降(P<0.01),Oxy-Hb血氧均值在左侧额叶通道14、22、24、43有显著下降(P<0.01),结论:多模块3D-VR记忆相关训练,对大脑左侧额中回、左内侧额上回、左额叶背外侧、右侧额中回(通道14、22、24、43),以上注意力、记忆力等认知相关脑区有显著激活。Objective:To observe the effect of multi-module 3D-VR memory-related training on brain function activation by functional near infrared spectroscopy(fNIRS).Methods:A total of 26 healthy subjects were recruited in this experiment,and each of them tried a 15-min multi-module 3D-VR memory-related training.All subjects were monitored by resting fNIRS for 10 min before and after the training.The frontal lobe blood oxygen signals were collected from all channels in the two tests,the beat value of frontal lobe blood oxygen concentration and the average value of blood oxygen signals were recorded,and the changes of frontal lobe function and its influence on cortical activation were compared and analyzed.Results:Compared with those before the test,the beta values of OXY-HB in frontal lobe in channels(14,22,24,43)were significantly different(P<0.05),and the mean values of blood oxygen signals in frontal lobe in channels(14,22,24,43)were significantly different(P<0.05).Conclusion:Multi-module 3D-VR memory-related training can significantly activate the left middle frontal gyrus,the left medial frontal gyrus,the left dorsolateral frontal gyrus and the right middle frontal gyrus(channels 14,22,24 and 43),and the above cognitive related brain regions such as attention and memory.

关 键 词：多模块3D虚拟现实技术 功能性近红外光谱技术 血氧浓度 皮层兴奋性 

分 类 号：R49[医药卫生—康复医学] R742[医药卫生—临床医学]