淋球菌、沙眼衣原体和解脲支原体三重感染患者流行病学调查及相关危险因素分析  

The epidemiological investigation and related risk factors of NGH、CT and UU triple infection

作　　者：张建营 茅利明 ZHANG Jianying;MAO Liming(Department of Clinical Laboratory,Shaoxing City Keqiao District Hospital of Traditional Chinese Medicine,Shaoxing 312030,China.)

机构地区：[1]绍兴市柯桥区中医医院检验科,浙江绍兴312030 [2]绍兴市中心医院医共体总院检验科

出　　处：《全科医学临床与教育》2024年第9期803-806,共4页Clinical Education of General Practice

摘　　要：目的 调查泌尿生殖道淋球菌(NGH)、沙眼衣原体(CT)和解脲支原体(UU)三重感染患者的流行病学特征,并对其进行相关危险因素的分析。方法 选择2021年6月至2023年5月在本院门诊采样的初诊疑似泌尿生殖系感染患者5 264例为研究对象,经PCR检测NGH、CT和UU均阳性的患者134例作为病例组,选取同时期在相关科室做NGH、CT和UU的检测且全阴性的86例作为对照组,对两组相关生殖道病原体检测数据进行统计学分析。结果 5 264例患者中,三重感染者的比例为2.55%。不同性别、户籍所在地、年龄、感染类型、临床症状、婚姻的三重感染患者比例比较,差异均有统计学意义(χ~2分别=11.94、161.42、65.64、77.37、67.51、5.53,P均<0.05),不同职业的三重感染患者比例比较,差异无统计学意义(χ~2=0.54,P>0.05)。多因素分析显示,性伴侣数>1个、性生活中无避孕措施、个人卫生情况差是三重感染发生的危险因素(OR分别=20.37、4.26、8.34,P均<0.05)。结论 疑似泌尿生殖系感染人群中NGH、CT、UU检出率整体较高,其三重感染患者呈现年轻低龄化趋势,应加强青壮年性传播疾病防治工作;同时临床需要重视混合感染的筛查,以免延误治疗。Objective To analyze the epidemiological investigation of triple infection of NGH,CT and UU,explore the related risk factors,and analyze the infection of other pathogens in these patients.Methods Totally 5264 pa⁃tients with suspected urogenital infection from June 2021 to May 2023 in our hospital were enrolled.The 134 cases with triple infection of NGH,CT and UU as case group,and the 86 cases with NGH,CT and UU negative at the same period in related departments as control group.The relevant reproductive tract pathogen detection data between two groups was analyzed.Results Among the 5264 patients,the proportion of triple infections was 2.55%.There were statistically significant differences in the proportion of triple infection patients of different genders,registered resi⁃dence locations,ages,infection types,clinical symptoms,and marriages(χ2=11.94,161.42,65.64,77.37,67.51,5.53,P<0.05),and there was no statistically significant difference in the proportion of triple infection patients of different occupations(χ2=0.54,P>0.05).The number of sexual partners>1,no contraceptive measures in sexual life,and poor personal hygiene were the risk factors for triple infection(OR=20.37,4.26,8.34,P<0.05).Conclusion The prevalence of NGH,CT and UU is high in the patients of genitourinary infection,the triple infected patients are lower⁃ing ages trends,so the prevention and treatment of sexually transmitted diseases in young adults should be strength⁃ened.At meanwhile,the detection about multiple pathogens should be appreciated by doctors in order to prevent misdi⁃agnosis and delayed treatment.

关 键 词：淋球菌 沙眼衣原体 解脲支原体 病原菌感染 

分 类 号：R446.5[医药卫生—诊断学]