子宫内膜容受性的研究进展  

Research progress of endometrial receptivity

作　　者：钟晓盈 贾雪敏 刘海元[1] ZHONG Xiao-ying;JIA Xue-min;LIU Hai-yuan(Department of Obstetrics&Gynecology,National Clinical Research Center for Obstetrics&Gynecologic Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院妇产科,国家妇产疾病临床医学研究中心,北京100730

出　　处：《生殖医学杂志》2024年第9期1250-1257,共8页Journal of Reproductive Medicine

摘　　要：囊胚与子宫内膜的协同作用是建立成功妊娠的必要条件,容受性佳的子宫内膜及良好的胚胎质量是胚胎移植成功的两大关键因素。随着辅助生殖技术的发展,子宫内膜容受性(ER)逐渐受到重视,特别是对于反复种植失败的患者来说,准确辨别子宫内膜容受时期可以协助评估种植窗,从而提高胚胎移植的成功率。子宫内膜相关疾病影响着众多不孕女性,尽管这类疾病与ER的相关性研究逐渐增多,但仍无国际公认的标准指导临床诊治,给不孕患者带来严重的心理及经济负担。本文从ER的临床应用出发,探讨ER的评估方法及不同子宫内膜相关疾病对ER的影响。The synergistic effect between blastocysts and endometrium is a necessary factor for establishing a successful pregnancy.The arrival of a viable embryo in the uterine cavity and endometrium in a state of receptivity are two essential prerequisites for successful embryo implantation.With the development of assisted reproductive technology,the concept of endometrial receptivity(ER)has been paid more and more attention.Especially for patients with recurrent implantation failure,accurate identification of the endometrial receptivity period can help evaluate the implantation window and improve the probability of embryo transfer.Many infertility results from endometrial related diseases.Although there are more and more studies on the related fields,there is still no internationally recognized standard to guide clinical diagnosis and treatment,which brings serious psychological and economic burdens to infertile women.Based on the clinical application of ER,this article discusses the evaluation methods of ER and the effect of endometrial-related diseases on ER.

关 键 词：子宫内膜容受性 胚胎移植 子宫内膜相关疾病 

分 类 号：R711.6[医药卫生—妇产科学]