益气涤痰通络汤治疗急性脑梗死(中经络气虚痰瘀证)的临床效果  

Clinical Effect of Yiqi Ditan Tongluo Decoction in the Treatment of Acute Cerebral Infarction(Zhongjingluo Qi Deficiency and Phlegm Stasis Syndrome)

作　　者：夏溪[1] 宋贯霞 朱洁[1] XIA Xi;SONG Guanxia;ZHU Jie(Jurong Hospital of Traditional Chinese Medicine,Jurong 212400,Jiangsu,China)

机构地区：[1]句容市中医院,江苏句容212400

出　　处：《世界复合医学》2024年第5期39-42,47,共5页World Journal of Complex Medicine

摘　　要：目的 探究益气涤痰通络汤用于急性脑梗死(acute cerebral infarct,ACI)(中经络气虚痰瘀证)患者临床治疗中的效果。方法 选取2021年10月—2023年10月句容市中医院收治的219例ACI(中经络气虚痰瘀证)患者为研究对象,根据不同的治疗方法分为对照组和观察组,对照组实施西医常规治疗(n=109),观察组在常规治疗基础上加用益气涤痰通络汤(n=110)。分析比较两组脑动脉血流动力学指标(搏动指数、动脉血流阻力指数)、血清黏附分子水平(可溶性血管细胞黏附分子、可溶性细胞间黏附因子-1)、神经缺损程度评分、残疾程度评分、中医证候积分、临床效果。结果 治疗2周后,观察组美国国立卫生研究院卒中量表评分、改良Rankin量表评分低于对照组,差异有统计学意义(P均<0.05)。治疗2周后,两组患者症状均明显减轻,且观察组中医证候积分下降幅度更大,差异有统计学意义(P均<0.05)。治疗2周后,观察组搏动指数、动脉血流阻力指数小于对照组,差异有统计学意义(P均<0.05)。治疗2周后,观察组血清黏附分子水平均低于对照组,差异有统计学意义(P均<0.05)。观察组治疗总有效率为96.36%(106/110),高于对照组的85.32%(93/109),差异有统计学意义(χ^(2)=8.045,P=0.005)。结论 对ACI(中经络气虚痰瘀证)患者行益气涤痰通络汤治疗疗效确切,可促进患者神经功能恢复,减轻症状表现。Objective To investigate the effect of Yiqi Ditan Tongluo Decoction in the clinical treatment of patients with acute cerebral infarction(ACI)(Zhongjingluo Qi deficiency and phlegm stasis syndrome).Methods From October 2021 to October 2023,219 patients with ACI(Zhongjingluo Qi deficiency and phlegm stasis syndrome) admitted to Jurong Hospital of Traditional Chinese Medicine were selected as the research objects.According to different treatment methods,they were divided into control group and observation group.The control group was treated with routine Western medicine(n=109),and the observation group was treated with Yiqi Ditan Tongluo Decoction(n=110) on the basis of routine treatment.The cerebral artery hemodynamics indexes(pulsitility index,arterial blood flow resistance index),serum adhesion molecule levels(soluble vascular cell adhesion molecule,soluble cell adhesion molecules-1),neurological deficit score,disability score,Traditional Chinese Medicine syndrome score and clinical effect were analyzed and compared between the two groups.Results After 2 weeks of treatment,the National Institutes of Health Stroke Scale score and Modified Rankin Scale score of the observation group were lower than those of the control group,and the differences were statistically significant(both P<0.05).After 2 weeks of treatment,the symptomatic manifestations of patients in both groups were significantly reduced,and the decrease in Traditional Chinese Medicine syndrome scores was greater in the observation group,and the differences were statistically significant(all P<0.05).After 2 weeks of treatment,the pulsitility index and arterial blood flow resistance index of the observation group were smaller than those of the control group,and the differences were statistically significant(both P<0.05).After 2 weeks of treatment,the serum adhesion molecule levels of the observation group were lower than those of the control group,and the differences were statistically significant(both P<0.05).The total effective rate of treatment in the o

关 键 词：益气涤痰通络汤 急性脑梗死 中经络气虚痰瘀证 

分 类 号：R4[医药卫生—临床医学]