补益药红芪免疫调节作用机制研究进展  

Research progress on immunomodulatory mechanism of Hedysari Radix

作　　者：燕羽婷 李昕蓉 李岩[1] 符凯润 谢鑫明 魏小成 何军刚 李成义[1] YAN Yuting;LI Xinrong;LI Yan;FU Kairun;XIE Xinming;WEI Xiaocheng;HE Jungang;LI Chengyi(Gansu University of Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000

出　　处：《中草药》2024年第16期5656-5668,共13页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(82160730);国家自然科学基金青年科学基金项目(82104345);甘肃省教育厅双一流重大科研项目(GSSYLXM-05);甘肃省科技计划项目(21YF5FA133)。

摘　　要：红芪作为甘肃道地药材,历史悠久、应用广泛、补治皆宜,具有补气升阳、固表止汗等功效。现代研究表明红芪的免疫调节药效显著,具备多组分、多机制、多通路协同作用的特色,可有效改善免疫器官形态功能,刺激免疫细胞增殖活化,调节免疫因子分泌释放,治疗多种免疫紊乱性疾病等。通过梳理整合红芪免疫调节作用的相关文献研究,归纳论述其调节免疫功能所涉及的作用机制,为拓宽延伸红芪的研究应用提供科学思路和理论依据。As a genuine medicinal material in Gansu province,Hongqi(Hedysari Radix)has a long history and is widely used,it is suitable for both supplementation and treatment,with effects of invigorating qi and ascending yang,consolidating exterior and stopping sweating.Modern research has proven that the immunomodulatory effects of Hedysari Radix are remarkable,exhibiting multi-component,multi-mechanism,and multi-pathway synergistic effects.It can effectively improve the morphology and function of immune organs,stimulate the proliferation and activation of immune cells,regulate the secretion and release of immune factors,and treat a variety of immune disorders.This paper summarizes and discusses the mechanism of action involved in the regulation of immune function by combining and integrating relevant literature research on the immunomodulatory effect of Hedysari Radix,aiming to provide scientific ideas and a theoretical basis for broadening the research applications of Hedysari Radix.

关 键 词：红芪 免疫调节 免疫细胞 补益类中药 药食同源 

分 类 号：R285[医药卫生—中药学]