三七皂苷成分及临床药理作用研究进展  

Research Progress on the Components and Clinical Pharmacological Effects of Panax Notoginseng Saponin

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作  者:郭玺 刘盼茹 唐乙朝 王海丹[2] 郭云柯[2] 殷爱玲[3] 李永明 胡静 周伟 虞鹤鸣 GUO Xi;LIU Panru;TANG Yizhao;WANG Haidan;GUO Yunke;YIN Ailing;LI Yongming;HU Jing;ZHOU Wei;YU Heming(National Key Laboratory of Multitarget Natural Medicines,School of Chinese Medicine,China Pharmaceutical University,Nanjing 210009,China;The Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210001,China;School of Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;The Affiliated Jiangyin Hospital of Nantong University,Wuxi 214499,China)

机构地区:[1]多靶标天然药物全国重点实验室,中国药科大学中药学院,江苏南京210009 [2]南京中医药大学附属医院,江苏南京210029 [3]南京中医药大学附属南京中医院,江苏南京210001 [4]南京中医药大学医学院,江苏南京210023 [5]南通大学附属江阴医院,江苏无锡214499

出  处:《南京中医药大学学报》2024年第9期985-992,共8页Journal of Nanjing University of Traditional Chinese Medicine

基  金:国家自然科学基金面上项目(82274071);江苏省中医药管理局科技发展重点项目(ZD202010)。

摘  要:三七作为传统中草药现已受到医药界的共同认可和关注,现代植物化学研究表明三七皂苷是三七的主要化学成分。现代药理研究及临床应用发现,其具有抗癌、抗氧化及治疗心血管疾病等作用。综述三七主要化学成分和药理作用的研究进展,以期为三七的临床应用及后期研究提供帮助。Notoginseng Radix et Rhizoma as a traditional Chinese herbal medicine has now been recognized and paid attention to by the pharmaceutical community.Modern phytochemical studies have shown that Panax notoginseng saponin is the main chemical component of Notoginseng Radix et Rhizoma.Modern pharmacological studies and clinical applications have revealed that it has anti-cancer,antioxidant and cardiovascular disease effects.In this study,we reviewed the research progress of the main chemical components and pharmacological effects of Notoginseng Radix et Rhizoma,with the aim of providing assistance for the clinical application and later studies of Notoginseng Radix et Rhizoma.

关 键 词:三七 三七皂苷 化学成分 临床应用 药理作用 

分 类 号:R285.5[医药卫生—中药学]

 

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