EO烷基化反应指示玻片的研制  

Development of an Indicating Slide for EO Alkylation Reaction

作　　者：黄悠然 陈玉放 曹立久 邱智杰 宗同强 Huang Youran;Chen Yufang;Cao Lijiu;Qiu Zhijie;Zong Tongqiang(CAS Testing Technical Services(Guangzhou)Co.,Ltd.,Guangzhou 510650,China)

机构地区：[1]中科检测技术服务(广州)股份有限公司,广东广州510650

出　　处：《广东化工》2024年第18期14-17,共4页Guangdong Chemical Industry

摘　　要：以NBP与EO的烷基化反应为机理,制备了一种可实时指示EO烷基化反应的简易指示玻片,考察了玻片油墨配方中NBP含量、碱性调节剂类型和含量以及薄膜厚度对指示玻片颜色和吸光度的影响,并用紫外-可见分光光度计表征。结果表明,在NBP含量为2%~3%、碱性调节剂三乙醇胺含量3%~4%、膜厚为150μm时,吸光度与反应时间近似呈线性关系。指示玻片通过光源和光敏电阻最终输出阻值信号,无需人工判读,未来可用于大批量EO灭菌过程中进行实时跟踪。Using the alkylation reaction of NBP with EO as the mechanism,a simple indicator slide that can indicate the alkylation reaction of EO in real time was prepared,and the color and absorbance effects of the NBP content,alkaline regulator,and film thickness were investigated and characterized by UV-visible spectrophotometer.The results showed that the absorbance was approximately linearly related to the reaction time at 2%~3%NBP content,3%~4%triethanolamine content,and 150μm film thickness.The indicator slide outputs resistance signal through light source and photoresistor.It can be future used in real-time high-volume EO sterilization tracking without manual reading.

关 键 词：环氧乙烷 烷基化反应 指示剂 灭菌 化学指示卡 

分 类 号：TH789[机械工程—仪器科学与技术]