IDEAL-IQ序列对膝骨关节炎膝周软组织脂肪浸润的定量评估价值  

The quantitative assessment value of the IDEAL-IQ sequence for knee osteoarthritis and surrounding soft tissue fat infiltration

作　　者：郝天琦 王雅妹 王国华[1] 杨雅晴 黄小铭 HAO Tianqi;WANG Yamei;WANG Guohua;YANG Yaqing;HUANG Xiaoming(Department of Radiology,Qingdao Municipal Hospital,Qingdao,Shandong Province 266011,China;Graduate School,Dalian Medical University,Dalian,Liaoning Province 116044,China;Department of Radiology,Qingdao Hiser Hospital Affiliated of Qingdao University,Qingdao,Shandong Province 266033,China)

机构地区：[1]青岛市市立医院放射科,山东青岛266011 [2]大连医科大学研究生院,辽宁大连116044 [3]青岛大学附属青岛市海慈医院放射科,山东青岛266033

出　　处：《实用放射学杂志》2024年第8期1329-1333,共5页Journal of Practical Radiology

摘　　要：目的探讨基于非对称回波的最小二乘估算法迭代水脂分离(IDEAL-IQ)定量技术测量膝骨关节炎(KOA)患者髌下脂肪垫(IPFP)及膝关节周围肌肉脂肪分数(FF)与KOA程度的价值。方法本研究共纳入患者106例,根据Kellgren-Lawrence分级(KLG)分为无KOA组、轻度KOA组和重度KOA组。应用IDEAL-IQ技术测量IPFP、膝关节周围肌肉FF值,分析FF值与KOA的相关性,评估其诊断KOA的价值。结果重度KOA组和轻度KOA组显示较低的IPFP FF值及较高的膝关节周围肌肉FF值。IPFP及膝关节周围部分肌肉[股内侧肌(VM)、股外侧肌(VL)、半膜肌(SE)、缝匠肌(SA)、腓肠肌内侧头(Gas(media))、腓肠肌外侧头(Gas(lateral))]FF值与KOA程度之间存在相关性(r/rs=-0.708、0.737、0.567、0.468、0.280、0.491、0.378),诊断KOA的曲线下面积(AUC)分别为0.850、0.950、0.842、0.759、0.692、0.763、0.725。结论IDEAL-IQ序列可对KOA患者IPFP及膝关节周围肌肉脂肪浸润定量评估,对KOA发展及严重程度的预测有一定的潜力。Objective To explore the value of measuring infrapatellar fat pad(IPFP)and muscle fat fraction(FF)around the knee joint based on iterative decomposition of water and fat with echo asymmetry and least squares estimation quantification(IDEAL-IQ)quantitative technology in patients with knee osteoarthritis(KOA)for the degree of KOA.Methods A total of 106 participants were included in this study.Participants were grouped based on Kellgren-Lawrence grading(KLG),divided into no KOA group,mild KOA group and severe KOA group.The IDEAL-IQ technology was used to measure FF values of IPFP and muscles around the knee joint,the correlation between FF values and KOA was analyzed,and its value in diagnosing KOA was evaluated.Results In severe KOA group and mild KOA group can be observed in the way of lower IPFP FF values and higher FF values muscles around the knee joint.The FF values of IPFP and part of the muscles around the knee joint[vastus medialis muscle(VM),vastus lateralis muscle(VL),semimembranosus(SE),sartorius(SA),medial head of gastrocnemius muscle(Gas(media)),lateral head of gastrocnemius muscle(Gas(lateral))]were correlated with the degree of KOA(r/rs=-0.708,0.737,0.567,0.468,0.280,0.491,0.378),the area under the curve(AUC)for diagnosing KOA were 0.850,0.950,0.842,0.759,0.692,0.763,and 0.725,respectively.Conclusion IDEAL-IQ sequence can quantitatively assess fat infiltration of IPFP and muscles around the knee joint in patients with KOA,and has certain potential to predict the development and severity of KOA.

关 键 词：膝关节 骨关节炎 髌下脂肪垫 脂肪分数 磁共振成像 IDEAL-IQ 

分 类 号：R684.3[医药卫生—骨科学] R445.2[医药卫生—外科学]