小剂量测试和高流速注射方案在甲状腺CT增强中的应用研究  

Application study of test bolus and high-flow rate injection scheme in thyroid CT enhancement

作　　者：林高雪 周燕[1] 王建伟[1] 陈骥梁 许晓泉[1] 徐露露[1] LIN Gaoxue;ZHOU Yan;WANG Jianwei;CHEN Jiliang;XU Xiaoquan;XU Lulu(Department of Radiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China;Application Training Department,Siemens Healthineers Digital Technology Co.,Ltd.,Shanghai 200000,China)

机构地区：[1]南京医科大学第一附属医院放射科,江苏南京210029 [2]西门子数字医疗科技(上海)有限公司应用培训部,上海200000

出　　处：《实用放射学杂志》2024年第8期1349-1353,共5页Journal of Practical Radiology

基　　金：江苏省高等学校基础科学(自然科学)研究面上项目(22KJB320005)。

摘　　要：目的探讨小剂量测试结合高流速注射方案在提高甲状腺CT增强图像质量中的应用价值。方法选取行甲状腺CT平扫+增强检查的患者126例,其中采用常规法检查患者63例(对照组),采用小剂量测试、高流速注射方案检查患者63例(实验组)。客观评价:比较2组动脉期图像的信噪比(SNR)、对比噪声比(CNR)、甲状腺强化率、甲状腺实质-癌差异、伪影指数(AI),2组静脉期图像的甲状腺强化率和对比剂剂量。统计学方法采用独立样本t检验或Mann-Whitney U检验。主观评价:对2组动脉期图像中甲状腺的显示按4分法评价并行Mann-Whitney U检验。结果实验组动脉期图像的SNR、CNR、甲状腺强化率、甲状腺实质-癌差异和AI均优于对照组(P<0.05);对照组、实验组的静脉期甲状腺强化率无统计学差异(P>0.05);实验组对比剂量低于对照组(P<0.01)。实验组动脉期图像的甲状腺显示评分高于对照组,差异有统计学意义(P<0.01)。结论利用小剂量测试结合高流速注射方案可以显著提高甲状腺CT增强的图像质量。Objective To explore the application value of test bolus combined with a high-flow rate injection scheme in improving the quality of thyroid CT enhancement images.Methods A total of 126 patients who underwent thyroid plain scan and enhanced CT were selected.Among them,63 underwent conventional examination methods(control group),while the remaining 63 patients received test bolus and high-flow rate injection scheme(experimental group).Objective evaluation included the signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),thyroid enhancement rate,thyroid parenchyma-cancer difference,artifact index(AI)of the two groups of arterial phase images,thyroid enhancement rate of the two groups of venous phase images,and contrast agent dose of the two groups were all compared.Statistical analysis was performed via independent sample t-test or Mann-Whitney U test.Subjective evaluation included the evaluation of thyroid display in two groups of arterial phase images was conducted via the 4-point method,followed by the implementation of the Mann-Whitney U test.Results The SNR,CNR,thyroid enhancement rate,thyroid parenchyma-cancer difference,and AI in the arterial phase images of the experimental group were all significantly superior to those of the control group(P<0.05).There was no statistically significant difference in the thyroid enhancement rate in the venous phase between control group and experimental group(P>0.05);The contrast agent dose of the experimental group was significantly lower than that of the control group(P<0.01).The thyroid display score observed in the arterial phase images of the experimental group was significantly higher than that of the control group(P<0.01).Conclusion Using a test bolus combined with a high-flow rate injection scheme can significantly improve the image quality of thyroid CT enhancement.

关 键 词：伪影 甲状腺 计算机体层成像 

分 类 号：R335[医药卫生—人体生理学]