A pair of nuclear factor Y transcription factors act as positive regulators in jasmonate signaling and disease resistance in Arabidopsis  

作　　者：Chuyu Lin Chenghao Lan Xiaoxiao Li Wei Xie Fucheng Lin Yan Liang Zeng Tao 

机构地区：[1]Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects,Institute of Biotechnology,Zhejiang University,Hangzhou 310058,China [2]State Key Laboratory for Managing Biotic and Chemical Treats to the Quality and Safety of Agro‐products,Institute of Biotechnology,Zhejiang University,Hangzhou 311400,China

出　　处：《Journal of Integrative Plant Biology》2024年第9期2042-2057,共16页植物学报（英文版）

基　　金：supported by National Natural Science Foundation of China(31970534);Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding(2021C02064);the National Youth Talent Support Program。

摘　　要：The plant hormone jasmonate(JA)regulates plant growth and immunity by orchestrating a genome-wide transcriptional reprogramming.In the resting stage,JASMONATE-ZIM DOMAIN(JAZ)proteins act as main repressors to regulate the expression of JA-responsive genes in the JA signaling pathway.However,the mechanisms underlying de-repression of JA-responsive genes in response to JA treatment remain elusive.Here,we report two nuclear factor Y transcription factors NF-YB2 and NF-YB3(thereafter YB2 and YB3)play key roles in such de-repression in Arabidopsis.YB2 and YB3 function redundantly and positively regulate plant resistance against the necrotrophic pathogen Botrytis cinerea,which are specially required for transcriptional activation of a set of JA-responsive genes following inoculation.Furthermore,YB2 and YB3 modulated their expression through direct occupancy and interaction with histone demethylase Ref6 to remove repressive histone modifications.Moreover,YB2 and YB3 physically interacted with JAZ repressors and negatively modulated their abundance,which in turn attenuated the inhibition of JAZ proteins on the transcription of JA-responsive genes,thereby activating JA response and promoting disease resistance.Overall,our study reveals the positive regulators of YB2 and YB3 in JA signaling by positively regulating transcription of JA-responsive genes and negatively modulating the abundance of JAZ proteins.

关 键 词：histone demethylase jasmonate response JAZ repressor necrotrophic resistance nuclear factor 

分 类 号：S432.23[农业科学—植物病理学]