妊娠期糖尿病孕中、晚期血糖控制水平与巨大儿的相关性研究  

Study on the correlation between blood glucose control level and fetal macrogenesis in the middle and late pregnancy of gestational diabetes mellitus

作　　者：宋巧玲 Song Qiaoling(Department of Obstetrics and Gynecology,The Second People's Hospital of Huadu District,Guangzhou 510850,China)

机构地区：[1]广州市花都区第二人民医院妇产科,广东广州510850

出　　处：《实用妇科内分泌电子杂志》2024年第19期36-38,42,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨妊娠期糖尿病(GDM)孕中、晚期血糖控制水平与巨大儿的相关性。方法回顾性调取本院病案系统内2021~2024年150例妊娠期糖尿病孕妇(GDM组)和150例为非GDM孕妇(非GDM组),收集孕中、晚期血糖水平,分析新生儿体重与血糖控制水平的关系。结果GDM组孕中、晚期的空腹血糖(FBG)、糖化血红蛋白(HbA1c)水平均明显高于非GDM组,新生儿出生体重(3.55±0.42)kg和巨大儿发生率12.0%均分别高于非GDM组的(3.11±0.12)kg、4.67%(P<0.05)。巨大儿组孕妇孕中、晚期的FBG、HbA1c水平均明显高于非巨大儿组(P<0.05)。Spearman相关分析显示,血清FBG、HbA1c与巨大儿的发生成正相关(P<0.05)。结论妊娠期糖尿病孕中、晚期的FBG和HbA1c均与孕妇娩出巨大儿有关,在孕期应加强对血糖的监测和处理,以降低巨大儿的发生率。Objective To explore the relationship between the level of blood glucose control in the middle and late pregnancy and macrosomia in pregnant women with diabetes mellitus(GDM).Methods We retrospectively collected 150 pregnant women with gestational diabetes(GDM group)and 150 non GDM pregnant women(non GDM group)from 2021 to 2024 in the medical record system of our hospital,collected blood glucose levels in the middle and late pregnancy,and analyzed the relationship between neonatal weight and blood glucose control level.Results The fasting blood glucose(FBG)and glycated hemoglobin(HbA1c)levels in the GDM group during mid to late pregnancy were significantly higher than those in the non GDM group.The birth weight of newborns(3.55±0.42)kg and the incidence of macrosomia(12.0%)were higher than those in the non GDM group(3.11±0.12)kg and 4.67%,respectively(P<0.05).The levels of FBG and HbA1c in pregnant women with macrosomia during the middle and late stages of pregnancy were significantly higher than those in the non macrosomia group(P<0.05).Spearman correlation analysis showed that serum FBG and HbA1c were positively correlated with the occurrence of macrosomia(P<0.05).Conclusion Both FBG and HbA1c in the second and third trimester of gestational diabetes mellitus are related to the birth of macrosomia.Blood glucose monitoring and management should be strengthened during pregnancy to reduce the incidence of macrosomia.

关 键 词：妊娠期糖尿病 血糖 巨大儿 

分 类 号：R714.256[医药卫生—妇产科学]