2013—2022年四川省报告当年即死亡HIV/AIDS患者特征及影响因素分析  

Analysis of the characteristics and related factors of HIV/AIDs patients who died in the same year of reporting in Sichuan Province from 2013 to 2022

作　　者：袁风顺 张灵麟[1] 何芳 梁姝[1] 徐梦娇 卓玛拉措 刘小锦 曾亚莉[1] 刘伦皓[1] 胡莹[1] YUAN Fengshun;ZHANG Linglin;HE Fang;LIANG Shu;XU Mengjiao;ZHUOMA Lacuo;LIU Xiaojin;ZENG Yali;LIU Lunhao;HU Ying(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心,成都610041

出　　处：《预防医学情报杂志》2024年第9期1049-1056,共8页Journal of Preventive Medicine Information

摘　　要：目的分析2013—2022年四川省新报告当年即死亡艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人的流行病学特征及其影响因素,为制定减少新报告病例过早死亡的防控措施提供科学依据。方法通过传染病报告数据库筛选出2013—2022年四川省当年报告即死亡的HIV/AIDS患者,利用SPSS 23.0软件进行分析,患者特征差异分析使用χ^(2)检验,二分类和无序多分类Logistic回归模型用于死亡的影响因素分析,检验水准为α=0.05。结果四川省2013—2022年报告当年即死亡HIV/AIDS患者18191例,占报告病例总数的8.2%;主要死因为艾滋病无关死亡(67.4%),其中呼吸系统疾病(30.8%)、肿瘤(20.9%)占比较高,艾滋病相关死亡占18.4%;死亡时间为31 d(IQR:8~86 d);多因素Logistic回归分析显示年龄≥30岁(均有OR>1,P<0.001)、男性(OR=1.60,95%CI:,P<0.001)、异性传播(OR=1.60,95%CI,P<0.001)的患者死亡概率较高;而文化程度较高(均有OR<1,95%CI:,P<0.001)、家政/家务/待业(OR=0.81,95%CI:,P<0.001)、自愿咨询检测(OR=0.53,95%CI:,P<0.001)、首次CD4检测结果≥200个/μl(均有OR<1,P<0.001)、接受抗病毒治疗(OR=0.22,95%CI:,P<0.001)的患者死亡概率较低;无序多分类Logistic回归模型显示,相较于未死亡患者,除婚姻状况、民族、传播途径外,不同死因死亡的风险因素基本一致。结论四川省报告当年即死亡患者的时间间隔短,影响因素复杂,既有年龄、性别等个人因素,又有感染途径、检测发现来源等HIV感染相关因素,需采取综合性防治措施,早发现、早诊断和早治疗,以降低新报告HIV/AIDS患者的死亡风险。Objective To analyze the epidemiological characteristics and related factors of HIV/AIDS patients who died in the same year of newly reported in Sichuan province from 2013 to 2022,so as to provide scientific basis for formulating prevention and control measures to reduce premature deaths of newly reported cases.Methods HIV/AIDS patients who died in the same year of the newly reported from 2013 to 2022 were screened through the infectious disease reporting database,analysis was conducted by using SPSS 23.0 software,and differences in patient characteristics were analyzed withχ^(2) test,binary,and unordered multiclass Logistic regression models were used to analyze the related factors of death.Results From 2013 to 2022,total of 18191 of HIV/AIDS patients died in the same year of reported in Sichuan Province,accounting for 8.2%of the total reported cases;The main cause of death was unrelated to AIDS(67.4%),of which respiratory diseases(30.8%)and tumors(20.9%)accounted for a high proportion,and AIDS related deaths accounted for 18.4%;The median time of death was 31 days(IQR:8-86 days);Multivariate logistic regression analysis showed that patients aged≥30 years(all with OR>1,P<0.001),male(OR=1.60,P<0.001),and heterosexual transmission(OR=1.60,P<0.001)had a higher probability of death;And with higher education levels(all with OR<1,P<0.001),housekeeping/household chores/unemployed(OR=0.81,P<0.001),voluntary counseling and testing(OR=0.53,P<0.001),first CD4 test results≥200cells/μl(all with OR<1,P<0.001),and received antiviral therapy(OR=0.22,P<0.001)had a lower probability of death;The unordered multiclass logistic regression model showed that compared to non deceased patients,the risk factors for death from different causes were basically the same,except for marital status,ethnicity,and transmission routes.Conclusions In Sichuan Province,the deceased patients’interval from diagnosis to death is short who died within the same year,and the influencing factors are complex.There are personal factors such as age and

关 键 词：HIV/AIDS 新报告 死亡 影响因素 

分 类 号：R512.91[医药卫生—内科学]