2005—2022年四川省射洪市报告15岁及以上HIV/AIDS患者死亡病例分析  

Analysis of deaths in HIV/AIDS patients aged 15 years and above reported in Shehong City from 2005 to 2022

作　　者：羊雨婷 唐凌云 唐丽 YANG Yuting;TANG Lingyun;TANG Li(Shehong Center for Disease Control and Prevention,Shehong 629200,Sichuan Province,China)

机构地区：[1]射洪市疾病预防控制中心,四川射洪629200

出　　处：《预防医学情报杂志》2024年第9期1096-1103,共8页Journal of Preventive Medicine Information

摘　　要：目的分析2005—2022年射洪市HIV/AIDS病例的死亡情况及影响因素,为控制艾滋病死亡提供依据。方法通过中国疾病预防控制信息系统,收集2005—2022年射洪市15岁以上HIV/AIDS死亡病例的相关信息,描述其死亡特点及死亡比例随时间变化趋势,并用Cox比例风险模型分析生存时间的影响因素,以P<0.05为差异有统计学意义。结果截至2022年12月31日,射洪市共报告15岁及以上HIV/AIDS死亡病例464例,平均确证年龄为(57.69±16.40)岁,平均死亡年龄为(59.55±15.93)岁。其中男性占87.07%,死亡时病程阶段为HIV占63.58%,初中以下文化程度占90.30%,农民及民工在所有职业中占65.30%,医疗机构就诊者检测发现占96.55%,首次CD4检测值小于200个/μl患者占67.24%,50岁以上死亡病例占67.24%,未进行抗病毒治疗者占43.53%。主要死因分类中艾滋病无关死亡占84.70%,2005—2022年死亡比例从25.00%下降至3.65%,平均存活时长从0.00月延长到27.67月。Cox回归模型分析显示,男性(HR=1.71)、AIDS(HR=1.68)、农民及民工职业(HR=1.60)、异性传播(HR=1.91)、医疗机构检测发现(HR=2.17)、确证时年龄在50岁以上(HR=2.08),有更高的死亡风险;首次CD4检测值200个/μl以上(HR=0.41)、抗病毒治疗(HR=0.09),有更低的死亡风险。结论射洪市近几年艾滋患者死亡病例逐年增加,死亡率逐年下降,应继续推进“早发现、早干预、随访到位”策略全面实施,尽早发现和治疗HIV/AIDS患者。Objective To analyze the death situation and influencing factors of HIV/AIDS cases in Shehong City from 2005 to 2022,and to provide evidence for the control of AIDS death.Methods Through the Chinese Disease Prevention and Control Information System,the relevant information of HIV/AIDS deaths over 15 years old in Shehong city from 2005 to 2022 was collected to describe the characteristics of death and the trend of death ratio over time.Cox proportional risk model was used to analyze the influencing factors of survival time,and the difference P<0.05 was considered statistically significant.Results As of December 31,2022,a total of 464 HIV/AIDS deaths aged 15 years and above were reported in Shehong City,with an average age of confirmation of(57.69±16.40)years and an average age of death of(59.55±15.93)years,87.07%of them were males,63.58%were HIV patients at the time of death,90.30%had a junior high school education,and65.30%were farmers and migrant workers.96.55%of those patients were detected by medical institutions,67.24%of patients with initial CD4 test value less than 200/μL,67.24%of patients over 50 years old died,43.53%of patients did not receive antiviral treatment.Among the main causes of death,non-AIDS-related deaths accounted for 84.70%,and the proportion of deaths decreased from 25.00%to 3.65%during 2005-2022,and the average survival time increased from 0.00 months to 27.67 months.Cox regression model analysis showed that male(HR=1.71),AIDS(HR=1.68),farmer and migrant worker occupation(HR=1.60),heterosexual transmission(HR=1.91),medical institution detection(HR=2.17),and age above 50 years old at the time of confirmation had a higher risk of death.The risk of death was lower with the first CD4 test of more than 200/μl(HR=0.41)and antiviral treatment(HR=0.09).Conclusions In recent years,the death rate of HIV patients in Shehong City has increased year by year,and the death rate has decreased year by year.It is necessary to continue to promote the full implementation of the strategy of“early detecti

关 键 词：艾滋病 HIV 死亡率 风险因素 

分 类 号：R512.91[医药卫生—内科学]