疏肝健脾汤治疗肝郁脾虚型功能性消化不良患者的效果  

Effects of Shugan Jianpi decoction in treatment of patients with functional dyspepsia of liver stagnation and spleen deficiency type

作　　者：杜艺婷 DU Yiting(Department of Gastroenterology of Jiangxi Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Nanchang 330006 Jiangxi,China)

机构地区：[1]江西省中西医结合医院消化内科,江西南昌330006

出　　处：《中国民康医学》2024年第19期110-112,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察疏肝健脾汤治疗肝郁脾虚型功能性消化不良患者的效果。方法:选取2020年9月至2022年9月该院收治的80例肝郁脾虚型功能性消化不良患者进行前瞻性研究,按照随机数字表法将其分为对照组和观察组各40例。对照组予以常规西药治疗,观察组在对照组基础上予以疏肝健脾汤治疗。比较两组临床疗效,治疗前后中医证候积分(胃脘胀痛、胁肋胀痛、便溏、情绪抑郁)、胃功能指标[胃动素(MTL)、胃蛋白酶原Ⅱ(PGⅡ)、胃泌素(GS)]水平,以及不良反应发生率。结果:观察组治疗总有效率为95.00%(38/40),高于对照组的75.00%(30/40),差异有统计学意义(P<0.05);两组胃脘胀痛、胁肋胀痛、便溏、情绪抑郁等中医证候积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组MTL、PGⅡ、GS水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:疏肝健脾汤治疗肝郁脾虚型功能性消化不良患者可提高临床疗效,降低中医证候积分,改善胃功能指标水平,效果优于单纯常规西药治疗。Objective:To observe effects of Shugan Jianpi decoction in treatment of patients with functional dyspepsia of liver stagnation and spleen deficiency type.Methods:A prospective study was conducted on 80 patients with functional dyspepsia of liver stagnation and spleen deficiency type admitted to this hospital from September 2020 to September 2022.According to the random number table method,they were divided into control group and observation group,40 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with Shugan Jianpi decoction on the basis of that of the control group.The clinical efficacy,the TCM syndrome scores(epigastric distending pain,hypochondriac distending pain,loose stool,emotional depression)and the gastric function indexes[motilin(MTL),pepsinogen II(PGII),gastrin(GS)]levels before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 95.00%(38/40),which was higher than 75.00%(30/40)of the control group,and the difference was statistically significant(P<0.05).The scores of TCM syndromes such as epigastric distending pain,hypochondrium distending pain,loose stool and emotional depression in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of MTL,PGII and GS in the two groups were higher than those before the treatment,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Shugan Jianpi decoction can improve the clinical efficacy,reduce the score of TCM syndromes and improve the levels of gastric function indexes in the patients with functional dyspepsia of liver stagnation a

关 键 词：功能性消化不良 肝郁脾虚型 疏肝健脾汤 胃功能 中医证候积分 不良反应 

分 类 号：R259[医药卫生—中西医结合]