环泊酚与丙泊酚麻醉在无痛胃肠镜检查中的应用效果比较  

Comparison of application effects of Ciprofol and Propofol anesthesia in painless gastrointestinal endoscopy

作　　者：张琪琪 ZHANG Qiqi(Department of Anesthesiology of the Second Hospital of Xuzhou Mining Group,Xuzhou 221011 Jiangsu,China)

机构地区：[1]徐州矿务集团第二医院麻醉科,江苏徐州221011

出　　处：《中国民康医学》2024年第19期149-151,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:比较环泊酚与丙泊酚麻醉在无痛胃肠镜检查中的应用效果。方法:回顾性分析2023年1月至2024年1月于该院行无痛胃肠镜检查的60例患者的临床资料,按照麻醉用药不同将其分为对照组和观察组各30例。观察组予以环泊酚联合舒芬太尼麻醉,对照组予以丙泊酚联合舒芬太尼麻醉,比较两组麻醉相关指标(麻醉诱导时间、苏醒时间)水平,不同时间[入室时(T_(0))、麻醉后5 min(T_(1))、检查结束时(T_(2))]膈肌运动指标[膈肌移动度(DE)、膈肌厚度变化率(DTF)]水平,不良反应发生率,以及麻醉满意度。结果:两组麻醉诱导时间、苏醒时间比较,差异均无统计学意义(P>0.05);T_(1)、T_(2)时,两组DE、DTF水平均低于T_(0)时,但观察组高于对照组,差异有统计学意义(P<0.05);两组术中低血压、窦性心动过缓发生率比较,差异均无统计学意义(P>0.05);观察组呼吸抑制、注射痛发生率均低于对照组,差异有统计学意义(P<0.05);观察组麻醉满意度为93.33%(28/30),高于对照组的70.00%(21/30),差异有统计学意义(P<0.05)。结论:环泊酚麻醉应用于无痛胃肠镜检查可改善膈肌运动指标水平,降低呼吸抑制、注射痛发生率,提高麻醉满意度,效果优于丙泊酚麻醉。The clinical data of 60 patients who underwent painless gastrointestinal endoscopy in this hospital from January 2023 to January 2024 were retrospectively analyzed.According to the different anesthetic drugs,they were divided into control group and observation group,30 cases in each group.The observation group was given Propofol combined with Ciprofol anesthesia,while the control group was given Propofol combined with Sufentanil anesthesia.The levels of anesthesia-related indexes(anesthesia induction time,recovery time),diaphragmatic movement indexes[diaphragmatic excursion(DE),diaphragmatic thickening fraction(DTF)]at different times[at the time of entering the room(T_(0)),5 min after anesthesia(T_(1)),and at the end of examination(T_(2))],the incidence of adverse reactions,and the anesthesia satisfaction were compared between the two groups.Results:There were no significant differences in the anesthesia induction time and the recovery time between the two groups(P>0.05).At T_(1) and T_(2),the levels of DE and DTF in the two groups were lower than those at T_(0),but those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of respiratory depression and injection pain in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the anesthesia satisfaction of the observation group was 93.33%(28/30),which was higher than 70.00%(21/30)of the control group,and the difference was statistically significant(P<0.05).Conclusions:The Ciprofol anesthesia in the painless gastrointestinal endoscopy can improve the levels of diaphragm movement indexes,reduce the incidence of respiratory depression and injection pain,and improve the anesthesia satisfaction.Moreover,it is superior to Propofol anesthesia.

关 键 词：环泊酚 丙泊酚 麻醉 无痛胃肠镜检查 呼吸抑制 膈肌运动 

分 类 号：R614[医药卫生—麻醉学]