催眠药物对高龄老年人日间嗜睡与认知功能的影响  

Effects of hypnotics on cognition function and daytime sleepiness in the elderly

作　　者：郑虹 齐振波 徐鹏[1] 徐杰[1] 于新宇 藏亚楠 张兆岩[1] ZHENG Hong;QI Zhenbo;XU Peng;XU Jie;YU Xinyu;ZANG Yanan;ZHANG Zhaoyan(Department of Geriatrics,the 960 Hospital of PLA,Jinan 250031,China;Health Company,the 71901 Force of PLA,Liaocheng 252000,China)

机构地区：[1]中国人民解放军第九六〇医院干部一科,山东省济南市250031 [2]中国人民解放军第71901部队卫生连,山东省聊城市252000

出　　处：《实用老年医学》2024年第9期936-939,共4页Practical Geriatrics

基　　金：军委后勤保障部保健专项课题(16BJZ50,22BJ248)。

摘　　要：目的 探讨高龄老年人长期应用催眠药物对日间嗜睡与认知功能的影响。方法 选取在我院住院的103例年龄≥80岁的高龄老年人为研究对象,按照是否服用催眠药物分为服用催眠药物组和对照组,利用MoCA和Epworth嗜睡量表(ESS)调查分析高龄老年人认知功能及日间嗜睡的情况。结果 2组高龄老年人白天嗜睡发生率差异没有统计学意义(P>0.05)。ESS得分显示,对照组在沉闷的公共场所和午餐后安静地坐着时重度嗜睡发生率显著高于服用催眠药物组(P<0.05)。MoCA得分显示,服用催眠药物组与对照组在(语言)命名上差异有统计学意义(P<0.05)。结论 高龄失眠老年人接受合理有效催眠药物治疗,对日间嗜睡和认知功能未造成不良影响,因此可使用催眠药物加强对高龄老年人睡眠问题的干预。Objective To investigate the effects of long-term use of hypnotics on daytime sleepiness and cognitive function in the elderly.Methods A total of 103 elderly patients aged≥80 years old who were hospitalized in our hospital were enrolled in this study.They were divided into the hypnotic group and the control group according to whether they took hypnotics.The cognitive function and daytime sleepiness in the two groups were assessed respectively by Montreal Cognitive Assessment Scale(MoCA)and Epworth Sleepiness Scale(ESS)and compared.Results The incidence of daytime sleepiness showed no significant difference between the two groups(P>0.05).The scores of ESS showed that the incidence rates of severe sleepiness in dull public places or while sitting quietly after lunch in the control group were significantly higher than those in the hypnotic group(P<0.05).The scores of MoCA showed that there was statistically significant difference in(language)naming between the hypnotic group and the control group(P<0.05).Conclusions Reasonable and effective hypnotic drug treatment for the elderly with insomnia has no adverse effect on cognitive function and daytime sleepiness,so hypnotic drugs can be used to strengthen the intervention of sleep problems in the elderly.

关 键 词：催眠药物 日间嗜睡 认知功能 高龄老人 

分 类 号：R256.23[医药卫生—中医内科学]