柴陈泽泻汤联合腕踝针治疗持续性姿势-感知性头晕临床研究  

Clinical Study on Combination Use of Chaichen Zexie Decoction and Wrist-Ankle Acupuncture for Persistent-Postural Perceptual Dizziness

作　　者：林书阳 陈妙 黄祖秀 周荣[1] 胡万华[1] LIN Shuyang;CHEN Miao;HUANG Zuxiu;ZHOU Rong;HU Wanhua(Wenzhou Traditional Chinese Medicine Hospital of Zhejiang Chinese Medical University,Wenzhou Zhejiang 325000,China)

机构地区：[1]浙江中医药大学附属温州市中医院,浙江温州325000

出　　处：《新中医》2024年第18期60-65,共6页New Chinese Medicine

基　　金：温州市科技局基础性公益科研项目(Y2023259)。

摘　　要：目的:观察柴陈泽泻汤联合腕踝针治疗持续性姿势-感知性头晕(PPPD)痰湿中阻证的临床疗效,以及对血清同型半胱氨酸(Hcy)、尿酸(UA)的影响。方法:选取60例PPPD痰湿中阻证患者,以随机数字表法分对照组与试验组各30例。对照组给予腕踝针治疗,试验组在对照组基础上给予柴陈泽泻汤治疗。2组均治疗4周。比较2组临床疗效,眩晕残障量表(DHI)、汉密尔顿焦虑量表-14 (HAMA-14)、汉密尔顿抑郁量表(HAMD)评分,血清Hcy、UA水平,以及不良反应发生率。结果:治疗4周后,试验组总有效率96.67%,高于对照组80.00%,差异有统计学意义(P<0.05)。治疗2周、4周后,2组DHI评分均较治疗前降低,试验组DHI评分均低于同期对照组,差异均有统计学意义(P<0.05)。治疗2周、4周后,2组HAMA-14、HAMD评分均较治疗前降低,试验组HAMA-14、HAMD评分均低于同期对照组,差异均有统计学意义(P<0.05)。治疗4周后,2组血清Hcy、UA水平均较治疗前降低,试验组血清Hcy、UA水平均低于对照组,差异均有统计学意义(P<0.05)。治疗期间,试验组不良反应发生率23.33%,对照组不良反应发生率20.00%,2组比较,差异无统计学意义(P>0.05)。结论:柴陈泽泻汤联合腕踝针治疗PPPD痰湿中阻证,可缓解眩晕症状及焦虑、抑郁情绪,下调血清Hcy、UA水平,安全性高。Objective:To observe the clinical effect of the combination use of Chaichen Zexie Decoction and wrist-ankle acupuncture on persistent-postural perceptual dizziness(PPPD)with phlegm-damp obstructing middle energizer syndrome and its effect on serum homocysteine(Hcy)and uric acid(UA).Methods:A total of 60 cases of PPPD patients with phlegm-damp obstructing middle energizer syndrome were selected and divided into the control group and the trial group according to the random number table method,with 30 cases in each group.The control group was treated with wrist-ankle acupuncture,and the trial group was additionally treated with Chaichen Zexie Decoction.Both groups were treated for four weeks.The clinical effects,scores of Dizziness Handicap Inventory(DHI),Hamilton Anxiety Scale-14(HAMA-14)and Hamilton Depression Scale(HAMD),levels of serum Hcy and UA,and incidence of adverse reactions were compared between the two groups.Results:After four weeks of treatment,the total effective rate in the trial group was 96.67%,higher than that of 80.00%in the control group,the difference being significant(P<0.05).After two and four weeks of treatment,the DHI scores in the two groups were lower than those before treatment,and the DHI score in the trial group was lower than that in the control group at the same time point,differences being significant(P<0.05).After two and four weeks of treatment,the scores of HAMA-14 and HAMD in the two groups were reduced when compared with those before treatment,and above two scores in the trial group were lower than those in the control group at the same time point,differences being significant(P<0.05).After four weeks of treatment,the levels of serum Hcy and UA in the two groups were lower than those before treatment,and the above two levels in the trial group were lower than those in the control group,differences being significant(P<0.05).During the treatment,the incidence of adverse reactions was 23.33%in the trial group and 20.00%in the control group,there being no significance in the differ

关 键 词：持续性姿势-感知性头晕 痰湿中阻证 柴陈泽泻汤 腕踝针 焦虑 抑郁 同型半胱氨酸 尿酸 

分 类 号：R255.3[医药卫生—中医内科学]