右心室改良心肌做功指数评估产科抗磷脂综合征累及胎儿右心室功能  

Right ventricle modified myocardial performance index for evaluating maternal obstetric antiphospholipid syndrome involving fetal right ventricular function

作　　者：孙心蕊 苏晓婷[1] 张楠[1] 李晶萱 钟文成 王志斌[2] 刘美新[1] SUN Xinrui;SU Xiaoting;ZHANG Nan;LI Jingxuan;ZHONG Wencheng;WANG Zhibin;LIU Meixin(Department of Obstetrical Ultrasound,the Affiliated Hospital of Qingdao University Ultrasonic Medical Center,Qingdao 266003,China;Department of Echocardiography,the Affiliated Hospital of Qingdao University Ultrasonic Medical Center,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院超声医学中心产科超声科,山东青岛266003 [2]青岛大学附属医院超声医学中心心脏超声科,山东青岛266003

出　　处：《中国介入影像与治疗学》2024年第9期545-548,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的观察右心室改良心肌做功指数(RV-Mod-MPI)评价产科抗磷脂综合征(OAPS)累及胎儿右心室功能的价值。方法前瞻性纳入45例OAPS孕妇(OAPS组)及60名健康孕妇(对照组),应用脉冲波多普勒(PW)分别采集胎儿三尖瓣、肺动脉瓣血流图像,获取其RV-Mod-MPI;记录晚孕期孕妇及新生儿资料并进行组间比较,绘制受试者工作特征曲线,计算曲线下面积(AUC),评估以胎儿RV-Mod-MPI预测OAPS组不良妊娠结局的效能。结果相比对照组,OAPS组胎儿RV-Mod-MPI较高,新生儿出生体质量及出生后1 min Apgar评分较低,而不良妊娠结局发生率较高(P均<0.05)。以胎儿RV-Mod-MPI预测OAPS组不良妊娠结局的AUC为0.726。结论胎儿RV-Mod-MPI可用于评价OAPS累及胎儿右心室功能并预测不良妊娠结局。Objective To observe the value of right ventricle modified myocardial performance index(RV-Mod-MPI)for evaluating maternal obstetric antiphospholipid syndrome(OAPS)involving fetal right ventricular function.Methods Forty-five pregnant women with maternal OAPS(OAPS group)and 60 healthy pregnant women(control group)were prospectively enrolled.Fetal RV-Mod-MPI was obtained with tricuspid and pulmonary valve flow images by applying pulsed wave Doppler(PW).Late pregnancy conditions and data of newborns after delivery were recorded.The indexes were compared between groups.Receiver operating characteristic curve was drawn,and the area under the curve(AUC)was used to assess the efficacy of fetal RV-Mod-MPI for predicting adverse pregnancy outcomes in OAPS group.Results Compared with those in control group,OAPS group had higher fetal RV-Mod-MPI values,lower newborn birth weight and lower Apgar score at 1 min after birth,as well as higher probability of adverse pregnancy outcomes(all P<0.05).The AUC of fetal RV-Mod-MPI for predicting adverse pregnancy outcome in OAPS group was 0.726.Conclusion RVMod-MPI could be used to evaluate maternal OAPS involving fetal right ventricular function and predict adverse pregnancy outcomes.

关 键 词：胎儿 抗磷脂综合征 心室功能 右 超声检查 产前 前瞻性研究 

分 类 号：R714.5[医药卫生—妇产科学] R540.45[医药卫生—临床医学]