柴胡皂苷的生物学功能研究进展  

Research progressin biological functions of saikosaponins

作　　者：袁林 李万利[1] 靳玮 王浩宇[1] 朱进华 YUAN Lin;LI Wanli;JIN Wei;WANG Haoyu;ZHU Jinhua(Institute of Animal Husbandry and Veterinary Medicine,Henan Academy of Agricultural Sciences,Zhengzhou 450002,China;Animal Quarantine Station of Henan Province,Zhengzhou 450002,China)

机构地区：[1]河南省农业科学院畜牧研究所,河南郑州450002 [2]河南省动物检疫总站,河南郑州450002

出　　处：《中国兽医学报》2024年第6期1307-1315,共9页Chinese Journal of Veterinary Science

基　　金：河南省重大专项资助项目(221100110200)。

摘　　要：柴胡在中医中的应用已有2000多年的历史,具有解表、清热、调肝气、升阳气的作用,其药用特性已在欧亚大陆和北非广泛使用。柴胡皂苷(尤其是柴胡皂苷a和柴胡皂苷d)作为柴胡中的主要生物活性化合物,具有抗炎、抗肿瘤、抗氧化、抗病毒、免疫调节和保肝等作用。本文对柴胡皂苷的药理活性、作用机制及应用现状进行综述,以期为柴胡的进一步研究和开发提供新的见解。Radix Bupleuri has been used in traditional Chinese medicine for over 2000 years with functions of relieving exterior syndrome,clearing heat,regulating liver-qi,and lifting yang-qi.Its medicinal properties have been widely used in Eurasia and North Africa.As the main bioactive compounds in Radix Bupleuri,saikosaponins(especially saikosaponin A and saikosaponin D)have anti-inflammatory,anti-tumor,antioxidant,antivirus,immune regulatory,and liver protective effects.This article reviews the pharmacological activity,mechanism of action,and current application status of saikosaponins,in order to provide new insights for further research and development of Radix Bupleuri.

关 键 词：柴胡皂苷 抗炎 免疫调节 神经调节 抗病毒 

分 类 号：S853.7[农业科学—临床兽医学]